28: The McCanns and friends (the latter known as the "Tapas Seven") arrive at Ocean Club, Praia da Luz. McCanns given apartment 5A, Rua Dr Agostinho da Silva.
c. 30: Staff leave visible note at swimming-pool reception asking that same table in resort's tapas restaurant be booked daily for 20:30 for McCanns and Tapas Seven, because they are leaving their children in the apartments. Restaurant is 82-metre walk (295 ft) from 5A.
3 May
14:29: Kate takes last-known photograph of Madeleine by the pool.
20:30: McCanns and Tapas Seven go to tapas restaurant.
21:05: Gerry checks on children in 5A.
21:15: "Tanner sighting": Jane Tanner of the Tapas Seven sees man carrying child.
21:30: Matthew Oldfield of the Tapas Seven checks on children in 5A but does not look fully inside the bedroom.
22:00: "Smith sighting": Martin Smith and family see man carrying child.
22:00: Kate checks on children; reports Madeleine missing.
7: PJ interview Kate and Gerry; Kate declines to answer questions.
9: McCanns return to UK.
Unknown: Martin Smith, of the "Smith sighting", sees Gerry carry his son from the plane, and reports to British police that he believes this was the man he saw in Praia da Luz. He later accepts that he was mistaken.
10: PJ leak that Madeleine's DNA was found in McCanns' rental car.
11: The Sun: "Brit Lab Bombshell: Car DNA is 100% Maddie's".
12: Businessman Brian Kennedy steps forward as benefactor to finance private investigation.
Unknown: Kennedy funds Clarence Mitchell as McCanns' spokesperson.
Late: Kate and twins drug-tested in the UK at McCanns' request; results negative.
October
2: Chief Inspector Gonçalo Amaral of the PJ removed from Portuguese inquiry.
Unknown: McCanns hire Dave Edgar, a private investigator.
1 May: McCanns release age-progressed image.
May: Gonçalo Amaral, inquiry's former coordinator, convicted of perjury in relation to another case.
9 Sept: McCanns obtain injunction against Amaral book.
Unknown: McCanns meet British home secretary Alan Johnson to request review. Johnson commissions "scoping report" from Jim Gamble, head of CEOP Command.
28 Apr: Bantam Press releases Madeleine by Kate McCann.
Mar: PJ begin case review.
11 May: While serializing Kate's book, The Sun publishes open letter requesting British police review. Home Secretary Theresa May speaks by telephone to CEO of News International and editor of The Sun.