| Portfolio | Minister | Took office | Left office | Party | |
|---|---|---|---|---|---|
| Minister of Agriculture, Livestock and Irrigation | 30 March 2018 | 1 February 2021 | NLD | ||
| Deputy Minister of Agriculture, Livestock and Irrigation | Hla Kyaw | 30 March 2018 | 1 February 2021 | USDP | |
| Minister of Border Affairs | Ye Aung, Lt. Gen. | 30 March 2018 | 1 February 2021 | Tatmadaw | |
| Deputy Minister of Border Affairs | Than Htut, Maj. Gen. | 30 March 2018 | 1 February 2021 | Tatmadaw | |
| Minister of Commerce | 30 March 2018 | 1 February 2021 | NLD | ||
| Deputy Minister of Commerce | Aung Htoo | 30 March 2018 | 1 February 2021 | Independent | |
| Minister of Construction | 30 March 2018 | 1 February 2021 | Independent | ||
| Deputy Minister of Construction | Kyaw Linn | 30 March 2018 | 1 February 2021 | Independent | |
| Minister of Defence | Sein Win, Lt. Gen. | 30 March 2018 | 1 February 2021 | Tatmadaw | |
| Deputy Minister of Defence | Myint Nwe, Rear Admiral | 30 March 2018 | 1 February 2021 | Tatmadaw | |
| Minister of Education | 6 April 2016 | 1 February 2021 | Independent | ||
| Deputy Minister of Education | Win Maw Tun | 30 March 2018 | 1 February 2021 | Independent | |
| Minister of Electricity and Energy | 30 March 2018 | 1 February 2021 | Independent | ||
| Deputy Minister of Electricity and Energy | Tun Naing, Dr. | 30 March 2018 | 1 February 2021 | NLD | |
Khin Maung Win | 31 October 2019 | 1 February 2021 | |||
| Minister of Ethnic Affairs | 30 March 2018 | 1 February 2021 | MNP | ||
| Deputy Minister of Ethnic Affairs | Hla Maw Oo | 15 October 2018 | 1 February 2021 | ||
| Minister of Finance and Planning | 30 March 2018 | 25 May 2018 | NLD | ||
Soe Win | 31 May 2018 | 1 February 2021 | Independent | ||
| Deputy Minister of Finance and Planning | Maung Maung Win | 30 March 2018 | 1 February 2021 | NLD | |
| 30 March 2018 | 1 February 2021 | Independent | |||
| Minister of Foreign Affairs | 30 March 2018 | 1 February 2021 | NLD | ||
| Minister of Health and Sports | 30 March 2018 | 1 February 2021 | Independent | ||
| Deputy Minister of Health and Sports | 2 July 2018 | 1 February 2021 | Independent | ||
| Minister of Home Affairs | Kyaw Swe, Lt. Gen. | 30 March 2018 | 4 February 2020 | Tatmadaw | |
Soe Htut, Lt. Gen. | 10 February 2020 | Incumbent | Tatmadaw | ||
| Deputy Minister of Home Affairs | Aung Thu, Maj. Gen | 28 May 2018 | 1 February 2021 | Tatmadaw | |
| Minister of Hotels and Tourism | 30 March 2018 | 1 February 2021 | Independent | ||
| Deputy Minister of Hotels and Tourism | Tin Latt | 31 October 2019 | 1 February 2021 | ||
| Minister of Industry | 30 March 2018 | 1 February 2021 | Independent | ||
| Minister of Information | Pe Myint, Dr. | 30 March 2018 | 1 February 2021 | Independent | |
| Deputy Minister of Information | 30 March 2018 | 1 February 2021 | Independent | ||
| Minister of International Cooperation | 30 March 2018 | 1 February 2021 | NLD | ||
| Deputy Minister of International Cooperation | 1 December 2020 | 1 February 2021 | Independent | ||
| Minister of Labour, Immigration and Population | 30 March 2018 | 1 February 2021 | USDP | ||
| Minister of Natural Resources and Environmental Conservation | 30 March 2018 | 1 February 2021 | Independent | ||
| Deputy Minister of Natural Resources and Environmental Conservation | Ye Myint Swe, Dr | 15 October 2018 | 1 February 2021 | ||
| Minister of the Office of the Union Government | 24 November 2017 | 19 November 2018 | Independent | ||
Min Thu | 29 November 2018 | 1 February 2021 | NLD | ||
| Deputy Minister of the office of the Union Government | Tin Myint | 2 January 2019 | 1 February 2021 | Tatmadaw | |
| Ministry of Investment and Foreign Economic Relations | 19 November 2018 | 1 February 2021 | Independent | ||
| Minister of the President's Office | 30 March 2018 | 1 February 2021 | NLD | ||
| Deputy Minister of President's Office | Min Thu | 30 March 2018 | 29 November 2018 | NLD | |
| Minister of Religious Affairs and Culture | 30 March 2018 | 1 February 2021 | USDP | ||
| Deputy Minister of Religious Affairs and Culture | Kyi Min | 15 October 2018 | 1 February 2021 | ||
| Minister of Social Welfare, Relief and Resettlement | Win Myat Aye, Dr. | 30 March 2018 | 1 February 2021 | NLD | |
| Deputy Minister of Social Welfare, Relief and Resettlement | 30 March 2018 | 1 February 2021 | Independent | ||
| Minister of State Counsellor’s Office | 30 March 2018 | 1 February 2021 | Independent | ||
| Deputy Minister of State Counsellor’s Office | Khin Maung Tin | 30 March 2018 | 1 February 2021 | Independent | |
| Minister of Transport and Communications | 30 March 2018 | 1 February 2021 | NLD | ||
| Deputy Minister of Transport and Communications | 30 March 2018 | 1 February 2021 | NLD | ||
| 30 March 2018 | 1 February 2021 | Independent | |||
| Union Auditor General | 30 March 2018 | 1 February 2021 | Independent | ||
| Union Attorney-General | 30 March 2018 | 1 February 2021 | Independent | ||
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