Terreulactone A is a meroterpenoid isolate of Aspergillus with anti-acetylcholinesterase activity.[2]

Terreulactone A
Names
IUPAC name
(1R,4R,13R,14R,16R)-13-hydroxy-16-methoxy-8-(4-methoxyphenyl)-4,14,19,19-tetramethyl-5,9,18-trioxapentacyclo[14.2.1.01,14.04,13.06,11]nonadeca-6(11),7-diene-10,15,17-trione
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C28H30O9/c1-23(2)27-12-11-24(3)26(32,25(27,4)21(30)28(23,34-6)22(31)37-27)14-17-19(36-24)13-18(35-20(17)29)15-7-9-16(33-5)10-8-15/h7-10,13,32H,11-12,14H2,1-6H3/t24-,25-,26+,27-,28-/m1/s1
    Key: AOFMVUCAUSHJLI-RKFAPSRVSA-N
  • C[C@@]12CC[C@]34[C@@]([C@@]1(CC5=C(O2)C=C(OC5=O)C6=CC=C(C=C6)OC)O)(C(=O)[C@](C3(C)C)(C(=O)O4)OC)C
Properties
C28H30O9
Molar mass 510.539 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References

edit
  1. ^ "KNApSAcK Metabolite Information - C00014910". www.knapsackfamily.com.
  2. ^ Kim, Won-Gon; Cho, Kyung-Mi; Lee, Chong-Kil; Yoo, Ick-Dong (April 2002). "Terreulactone A, a novel meroterpenoid with anti-acetylcholinesterase activity from Aspergillus terreus". Tetrahedron Letters. 43 (17): 3197–3198. doi:10.1016/S0040-4039(02)00465-3.