Thallium(III) acetate is the acetate salt of thallium, with the chemical formula Tl(CH3COO)3. As a selective culture medium in microbiology,[1] thallium acetate is toxic,[2] but it can also be used as a hair loss agent. Koremlu, a depilatory that contained the rat poison Thallium acetate was widely marketed during th 1930s. Women who suffered the side effects of the popular product sued the company forcing it to bankruptcy in 1932. A dose of 8 mg/kg will cause acute poisoning, and the minimum lethal dose for adults is 12 mg/kg.[3]
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| IUPAC name
Thallium(III) acetate
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3D model (JSmol)
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| ECHA InfoCard | 100.018.104 |
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CompTox Dashboard (EPA)
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| Properties | |
| Tl(C2H3O2)3 | |
| Molar mass | 381.52 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Preparation
editThallium acetate can be obtained by reacting 80% acetic acid with thallium(III) oxide, and the product crystallizes in acetic anhydride.[4]
Properties
editAnhydrous thallium(III) acetate crystallises in the monoclinic system with space group C2/c. The unit cell dimensions are a = 15.54 Å b = 8.630 Å and c = 7.848 Å with β = 113.92°. There are four formula per unit cell. and density is 2.57. Three acetate ions are chellated to each thallium ion.[5]
Thallium(III) acetate monohydrate also crystallises in the monoclinic system with space group C2/c, a = 9.311 Å, b = 14.341 Å, c = 9.198 Å, β = 119.69 °. Unit cell volume is V = 1067.0 Å3 Z = 4, density is 2.49.[6]
References
edit- ^ Bulich, Anthony A.; Hartman, Paul A. (Nov 1969). "Evaluation of Thallium Acetate-Citrate Medium for Isolation of Enterococci". Applied Microbiology. 18 (5): 944–945. doi:10.1128/am.18.5.944-945.1969. ISSN 0003-6919. PMC 378124. PMID 5370465.
- ^ World Health Organization (2008). Anthrax in humans and animals. World Health Organization. pp. 139–. ISBN 978-92-4-154753-6. Archived from the original on 2014-06-28. Retrieved 23 February 2011.
- ^ "铊、玻璃和人——从两桩铊中毒事件说起". 中国科学院上海硅酸盐研究所. Archived from the original on 2015-05-20. Retrieved 2015-05-20.
- ^ Kolling, Orland W.; Mawdsley, Elizabeth A. (1971). "Anhydrous Thallium(III) Acetate". Transactions of the Kansas Academy of Science. 74 (1): 38. doi:10.2307/3627666. JSTOR 3627666.
- ^ Faggiani, R.; Brown, I. D. (1 September 1978). "Thallium(III) triacetate". Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 34 (9): 2845–2846. Bibcode:1978AcCrB..34.2845F. doi:10.1107/S0567740878009358.
- ^ Faggiani, R.; Brown, I. D. (15 September 1982). "Thallium triacetate monohydrate". Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 38 (9): 2473–2475. Bibcode:1982AcCrB..38.2473F. doi:10.1107/S0567740882009091. S2CID 97594213.