Thebe may refer to:
- Any of several female characters in Greek mythology - see List of mythological figures named Thebe
- Any of several cities known as Thebes in English - see Thebes (disambiguation)
- Thebe (moon), a moon of Jupiter
- Thebe (currency), 1/100 of a Botswana pula
- Thebe, an Amazon
- Thebe, alternate name for the Titaness Phoebe
- Thebe of Pherae, daughter of Jason of Pherae and wife of Alexander of Pherae
- Thebe Hypoplakia, a city in ancient Anatolia
- Thebe Magugu, South African fashion designer
- Thebe Medupe, South African astrophysicist
- Earl Sweatshirt, American musician