Thetapapillomavirus is a genus of viruses in the family Papillomaviridae.[1] Birds serve as natural hosts. There is only one species in this genus: Thetapapillomavirus 1. Diseases associated with this genus include cutaneous lesions.[2][3]
| Thetapapillomavirus | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Monodnaviria |
| Kingdom: | Shotokuvirae |
| Phylum: | Cossaviricota |
| Class: | Papovaviricetes |
| Order: | Zurhausenvirales |
| Family: | Papillomaviridae |
| Genus: | Thetapapillomavirus |
Structure
editViruses in Thetapapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 52-55 nm. Genomes are circular, around 78kb in length. The genome has 7 open reading frames.[2]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Thetapapillomavirus | Icosahedral | T=7 | Non-enveloped | Circular | Monopartite |
Life cycle
editViral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Birds serve as the natural host. Transmission routes are contact.[2]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Thetapapillomavirus | Birds | Epithelial: mucous; epithelial: skin | Cell receptor endocytosis | Lysis | Nucleus | Nucleus | Contact |
References
edit- ^ Van Doorslaer, K; Chen, Z; Bernard, HU; Chan, PKS; DeSalle, R; Dillner, J; Forslund, O; Haga, T; McBride, AA; Villa, LL; Burk, RD; ICTV Report Consortium (August 2018). "ICTV Virus Taxonomy Profile: Papillomaviridae". The Journal of General Virology. 99 (8): 989–990. doi:10.1099/jgv.0.001105. PMC 6171710. PMID 29927370.
- ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
- ^ "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 10 May 2021.