Thirkleby may refer to:

  • Thirkleby High and Low with Osgodby, a civil parish in Hambleton District, North Yorkshire, England, which includes the villages of Great Thirkleby and Little Thirkleby
  • Thirkleby, Kirby Grindalythe, a hamlet in the parish of Kirby Grindalythe, Ryedale District, North Yorkshire, from which Roger of Thirkleby's name was derived.

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