Thomas or Tom Blackwell may refer to:
- Thomas Blackwell (principal) (1660–1728), principal of Marischal College
- Thomas Blackwell (scholar) (1701–1757), Scottish classical scholar, son of above
- Thomas Evans Blackwell (1819–1863), English civil engineer
- Thomas Blackwell (fl. 1830), British co-founder of Crosse & Blackwell
- Tom Blackwell (1938–2020), American photorealist painter
- Thomas W. Blackwell (1958–2017), American politician