Tom Spencer may refer to:
- Tom Spencer (rugby league) (born 1991), English rugby league footballer
- Tom Spencer (baseball) (born 1951), American former Chicago White Sox outfielder and minor league baseball manager
- Tom Spencer (cricketer) (1914–1995), British cricketer and international umpire
- Tom Spencer (politician) (1948–2023), British Conservative Member of the European Parliament
- Tom Spencer (musician) (born 1967), British singer and guitarist for The Professionals and The Yo Yos
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