Transmembrane protein 57

Transmembrane protein 57 is a protein that in humans is encoded by the TMEM57 gene.

MACO1
Identifiers
Aliases	MACO1, MACOILIN, transmembrane protein 57, macoilin 1, TMEM57
External IDs	OMIM: 610301; MGI: 1913396; HomoloGene: 14449; GeneCards: MACO1; OMA:MACO1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1p36.11|1p36.11 Start 25,430,858 bp End 25,500,209 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4 D3|4 67.11 cM Start 134,530,070 bp End 134,580,656 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tendon of biceps brachii ganglionic eminence buccal mucosa cell Skeletal muscle tissue of biceps brachii body of pancreas gastrocnemius muscle islet of Langerhans muscle of thigh Achilles tendon liver Top expressed in superior cervical ganglion Rostral migratory stream hand Gonadal ridge spermatocyte zygote ganglionic eminence otolith organ lacrimal gland utricle More reference expression data BioGPS n/a
Gene ontology Molecular function molecular function microtubule binding actin filament binding Cellular component integral component of membrane neuron projection axon cell projection synapse nuclear membrane neuron projection terminus membrane nucleus endoplasmic reticulum rough endoplasmic reticulum membrane Biological process brain development neuronal signal transduction chemotaxis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55219 66146 Ensembl ENSG00000204178 ENSMUSG00000028826 UniProt Q8N5G2 Q7TQE6 RefSeq (mRNA) NM_001282564 NM_018202 NM_025382 NM_001355499 NM_001355500 NM_001355501 RefSeq (protein) NP_001269493 NP_060672 NP_079658 NP_001342428 NP_001342429 NP_001342430 Location (UCSC) Chr 1: 25.43 – 25.5 Mb Chr 4: 134.53 – 134.58 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

See also

• Endoplasmic reticulum protein 57 (Erp57)
• Vicinal (chemistry)

Further reading

• Aulchenko YS, Ripatti S, Lindqvist I, Boomsma D, Heid IM, Pramstaller PP, Penninx BW, Janssens AC, Wilson JF, Spector T, Martin NG, Pedersen NL, Kyvik KO, Kaprio J, Hofman A, Freimer NB, Jarvelin MR, Gyllensten U, Campbell H, Rudan I, Johansson A, Marroni F, Hayward C, Vitart V, Jonasson I, Pattaro C, Wright A, Hastie N, Pichler I, Hicks AA, Falchi M, Willemsen G, Hottenga JJ, de Geus EJ, Montgomery GW, Whitfield J, Magnusson P, Saharinen J, Perola M, Silander K, Isaacs A, Sijbrands EJ, Uitterlinden AG, Witteman JC, Oostra BA, Elliott P, Ruokonen A, Sabatti C, Gieger C, Meitinger T, Kronenberg F, Döring A, Wichmann HE, Smit JH, McCarthy MI, van Duijn CM, Peltonen L (2009). "Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts". Nat. Genet. 41 (1): 47–55. doi:10.1038/ng.269. PMC 2687074. PMID 19060911.
• Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.