Tricin synthase (EC 2.1.1.175, ROMT-17, ROMT-15, HvOMT1, ZmOMT1) is an enzyme with systematic name S-adenosyl-L-methionine:tricetin 3',5'-O-dimethyltransferase.[1][2] This enzyme catalyses the following chemical reaction
| Tricin synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.175 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- 2 S-adenosyl-L-methionine + tricetin 2 S-adenosyl-L-homocysteine + 3',5'-O-dimethyltricetin (overall reaction)
- (1a) S-adenosyl-L-methionine + tricetin S-adenosyl-L-homocysteine + 3'-O-methyltricetin
- (1b) S-adenosyl-L-methionine + 3'-O-methyltricetin S-adenosyl-L-homocysteine + 3',5'-O-dimethyltricetin
The enzymes from Oryza sativa (ROMT-15 and ROMT-17) catalyses the stepwise methylation of tricetin to its 3'-mono- and 3',5'-dimethyl ethers.
References
edit- ^ Lee, Y.J.; Kim, B.G.; Chong, Y.; Lim, Y.; Ahn, J.H. (2008). "Cation dependent O-methyltransferases from rice". Planta. 227: 641–647. doi:10.1007/s00425-007-0646-4. PMID 17943312.
- ^ Zhou JM, Fukushi Y, Wollenweber E, Ibrahim RK (2008). "Characterization of two O-methyltransferase-like genes in barley and maize". Pharm. Biol. 46: 26–34. doi:10.1080/13880200701729745.
External links
edit- Tricin+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
