Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific)

Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) (EC 2.5.1.89) is an enzyme with systematic name geranylgeranyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 7 isopentenyl units).[1] This enzyme catalyses the following chemical reaction

Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific)
Identifiers
EC no.2.5.1.89
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins
geranylgeranyl diphosphate + 7 isopentenyl diphosphate 7 diphosphate + tritrans,heptacis-undecaprenyl diphosphate

This enzyme is involved in the biosynthesis of the glycosyl carrier lipid in some archaebacteria.

References

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  1. ^ Hemmi H, Yamashita S, Shimoyama T, Nakayama T, Nishino T (January 2001). "Cloning, expression, and characterization of cis-polyprenyl diphosphate synthase from the thermoacidophilic archaeon Sulfolobus acidocaldarius". Journal of Bacteriology. 183 (1): 401–4. doi:10.1128/JB.183.1.401-404.2001. PMC 94892. PMID 11114943.
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