TyrT operon

The tyrT operon is a series of genes encoding the tRNA for tyrosine in Escherichia coli. It is activated in response to amino acid starvation.^[1]

Components

The tyrT operon consists of an upstream activation sequence, the gene for the tyrosine tRNA called tRNA₁^Tyr, and an RNA called rtT RNA which has an unknown function.^[1]

Regulation

Transcription of the tyrT operon is activated by the stringent response.^[1] Binding of the FIS protein to the operon's upstream activation sequence tightly bends the DNA, promoting transcription.^[2]

References

^ ^a ^b ^c Bosl M, Kersten H (1991). "A novel RNA product of the tyrT operon of Escherichia coli". Nucleic Acids Research. 19 (21): 5863–5870. doi:10.1093/nar/19.21.5863. PMC 329039. PMID 1840671.
^ Travers A, Schneider R, Muskhelishvili G (February 2001). "DNA supercoiling and transcription in Escherichia coli: the FIS connection". Biochimie. 83 (2): 213–217. doi:10.1016/s0300-9084(00)01217-7. PMID 11278071.

[Bosl-1] Bosl M, Kersten H (1991). "A novel RNA product of the tyrT operon of Escherichia coli". Nucleic Acids Research. 19 (21): 5863–5870. doi:10.1093/nar/19.21.5863. PMC 329039. PMID 1840671.

[Travers-2] Travers A, Schneider R, Muskhelishvili G (February 2001). "DNA supercoiling and transcription in Escherichia coli: the FIS connection". Biochimie. 83 (2): 213–217. doi:10.1016/s0300-9084(00)01217-7. PMID 11278071.

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