u-CARE otherwise known as user-friendly Comprehensive Antibiotic resistance Repository of Escherichia coli is a database focused on the documentation of multi-drug resistant Escherichia coli (E.coli)[1][2]. This database aims to provide a tool that is easily accessible to researchers unfamiliar with bioinformatics and to medical practitioners as a reference for which antibiotic to use/not use in the treatment of an E.coli infection.[1] u-CARE is manually curated with 52 antibiotics, 107 genes, transcription factors, and SNP.[1] Information provided include resistance mechanism for the gene and summary, chemical description, and structural descriptions for the antibiotic.[1] On the antibiotic page, there is an external link linking to public databases like GO, CDD, Ecocyc, DEG, KEGG, DrugBank, Pubchem and Uniprot.[1] u-CARE can be accessed at http://www.e-bioinformatics.net/ucare..

u-CARE
Content
DescriptionDatabase focused on documentation of multi-drug resistant Escherichia coli.
Data types
captured
E.coli
OrganismsBacteria
Contact
Research centerSam Higginbottom University of Agriculture, Technology and Sciences
Primary citationPMID 25935546
Access
Websitewww.e-bioinformatics.net/ucare.
Miscellaneous
Bookmarkable
entities
yes

See also

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References

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  1. ^ a b c d e Saha, Saurav B; Uttam, Vishwas; Verma, Vivek (2015-05-02). "u-CARE: user-friendly Comprehensive Antibiotic resistance Repository ofEscherichia coli". Journal of Clinical Pathology. 68 (8): 648–651. doi:10.1136/jclinpath-2015-202927. ISSN 0021-9746. PMID 25935546. S2CID 206985362.
  2. ^ "AMR Curation". GitHub.