In enzymology, an UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase (EC 2.6.1.34) is an enzyme that catalyzes the chemical reaction
| UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.6.1.34 | ||||||||
| CAS no. | 37277-89-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose + 2-oxoglutarate UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + L-glutamate
Thus, the two substrates of this enzyme are UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose and 2-oxoglutarate, whereas its two products are UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose and L-glutamate.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose:2-oxoglutarate aminotransferase. Other names in common use include uridine diphospho-4-amino-2-acetamido-2,4,6-trideoxyglucose, and aminotransferase. It employs one cofactor, pyridoxal phosphate.
References
edit- Distler J, Kaufman B, Roseman S (1966). "Enzymic synthesis of a diamino sugar nucleotide by extracts of type XIV Diplococcus pneumoniae" (PDF). Arch. Biochem. Biophys. 116 (1): 466–78. doi:10.1016/0003-9861(66)90054-3. hdl:2027.42/33501. PMID 4381351.
