USS Jefferson may refer to the following ships operated by the United States:
- USRC Jefferson (1802), a revenue cutter that served from 1802 until 1817
- USS Jefferson (1814), brig that served from 1814 until 1825
- USRC Jefferson (1832), a revenue cutter that served from 1833 until 1847; her named was changed to Crawford in 1839
- USRC Jefferson (1845), a revenue cutter that was transferred to the US Coastal Survey in 1848 and wrecked in Patagonia in 1851
See also
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This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.