Two ships of the United States Navy have borne the name USS Manchester, named in honor of the city of Manchester, New Hampshire.
- USS Manchester (CL-83) was a Cleveland-class light cruiser, launched in 1946 and struck in 1960
- USS Manchester (LCS-14) is an Independence-class littoral combat ship, launched in 2016
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.