USS Osceola has been the name of more than one United States Navy ship, and may refer to:
- USS Osceola (1863), a gunboat in commission from 1864 to 1865
- USS Osceola, a monitor which carried that name from 1869 to 1873 and had been named USS Neosho from 1863 to 1869 and USS Vixen briefly in 1869.
- USS Osceola (AT-47), an armed seagoing tug in commission in 1898 (seeing combat in the Spanish–American War) and from 1911 to 1922
- USS Osceola (YT-129), later YTB-129, later YTM-129, a harbor tug commissioned in 1938 and sold for scrapping in 1973
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.