USS Pearl has been the name of more than one United States Navy ship, and may refer to:
- USS Pearl (PF-88), a patrol frigate transferred to the United Kingdom while under construction which served in the Royal Navy as HMS Seychelles (K592) from 1944 to 1946
- USS Pearl (SP-1219), a patrol vessel in commission from 1917 to 1918
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.