Ungiminorine is an acetylcholinesterase inhibitor isolated from Narcissus.[1]

Ungiminorine
Names
IUPAC name
(1S,16R,17R,18S,19S)-17-methoxy-5,7-dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-2,4(8),9,14-tetraene-16,18-diol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C17H19NO5/c1-21-17-15(19)9-2-3-18-6-8-4-11-12(23-7-22-11)5-10(8)13(14(9)18)16(17)20/h2,4-5,13-17,19-20H,3,6-7H2,1H3/t13-,14+,15+,16-,17-/m0/s1
    Key: ZQLQBAUVRGDBJL-BIVLZKPYSA-N
  • InChI=1/C17H19NO5/c1-21-17-15(19)9-2-3-18-6-8-4-11-12(23-7-22-11)5-10(8)13(14(9)18)16(17)20/h2,4-5,13-17,19-20H,3,6-7H2,1H3/t13-,14+,15+,16-,17-/m0/s1
    Key: ZQLQBAUVRGDBJL-BIVLZKPYBI
  • CO[C@@H]1[C@H]([C@@H]2[C@H]3C(=CCN3CC4=CC5=C(C=C24)OCO5)[C@H]1O)O
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References

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  1. ^ Ingkaninan, K.; Hazekamp, A.; de Best, C. M.; Irth, H.; Tjaden, U. R.; van der Heijden, R.; van der Greef, J.; Verpoorte, R. (June 2000). "The application of HPLC with on-line coupled UV/MS-biochemical detection for isolation of an acetylcholinesterase inhibitor from narcissus 'Sir Winston Churchill'". Journal of Natural Products. 63 (6): 803–806. doi:10.1021/np9905719. ISSN 0163-3864. PMID 10869205.