Universidad de San Carlos may refer to:
- Universidade Federal de São Carlos, in São Carlos, Brazil
- University of San Carlos of Guatemala, based in Guatemala City
- Universad de San Carlos (Guatemalan football club), based in Guatemala City and commonly known as USAC
- Universidad San Carlos (Paraguay), based in Asunción, Paraguay.
- University of San Carlos, in Cebu, Philippines
This disambiguation page lists articles associated with the title Universidad de San Carlos.
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