Prof. Dr. Aamer Saeed Bhatti

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Prof. Dr. Aamer Saeed Bhatti
Born(1964-09-10)September 10, 1964
Pakistan
NationalityPakistani
EducationPh.D.
OccupationProfessor
Websitehttps://chem.qau.edu.pk/chem/index.php/dr-aamer-saeed-bhatti

(Chemist)

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Introduction

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Aamer Saeed Bhatti.[1] (Urdu: عامر سعید بھٹی; b. 10th September 1964, Jhelum, Punjab), recipient of the Tamgha-e-Imtiaz[2], Fellow of the Royal Society of Chemistry (FRSC), with an h-index of 47 and 11,335 citations, is a Pakistani organic chemist currently serving as the Dean and Tenured Professor of Chemistry at the Department of Chemistry[3], Quaid-I-Azam University[4], Islamabad, Pakistan. He has served as Chairman (2021–2024) Department of Chemistry[5], Quaid-I-Azam University, Islamabad, Pakistan. He contributed to the development of the Chemical Sciences at the Department of Chemistry, Quaid-I-Azam University, and transformed the landscape of higher education. He has published more then 620 research publications in renowned journals, 7 international patents, 11 book chapters, and two books. He has supervised more than 72 masters and 28 Ph.D. students. He is a Fellow of the Royal Society of Chemistry FRSC (UK), a Fellow of the Chemical Society of Pakistan[6], a Fellow Pakistan Academy of Sciences[7], and a Professor at Quaid-I-Azam University, Islamabad. He was ranked among the world's top 2% scientists by Stanford University in 2020[8], and again in 2022 by Stanford University & Elsevier[9]

Education

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Dr. Bhatti is a distinguished scholar in Organic Chemistry, recognized for his academic excellence and significant research contributions. He earned his M.Sc. in Organic Chemistry from Quaid-i-Azam University, Islamabad, in 1986, where he conducted research on the chemical properties of the plant *Ipomoea carnea* under the guidance of Prof. Dr. Naeema Khan. Continuing his studies at the same institution, he completed his M.Phil. in 1988, with a thesis focused on developing a synthetic approach to the Isochroman system, contributing to the study of fungal metabolites.

In 1994, Dr. Bhatti received his Ph.D. in Organic Chemistry from Quaid-i-Azam University, where his doctoral research, supervised by Prof. Dr. Nasim H. Rama, involved the synthesis of natural compounds such as Isocoumarins. His research, conducted between 1987 and 1994, was part of NSRD B+ and PSF projects.

From 1994 to 1995, Dr. Bhatti conducted further research at his alma mater, focusing on the total synthesis of Feralolide. He was also awarded Alexander von Humboldt Post-Doctoral Fellowships in 2001 and 2020, which enabled him to carry out postdoctoral research at the Institute für Organische Chemie at Universität Hannover, Germany, under the supervision of Prof. Dr. Markus Kalesse.

Research Work

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Prof. Dr. Aamer Saeed Bhatti's research covers diverse areas of synthetic bioorganic and medicinal chemistry, with a focus on natural products and heterocyclic chemistry. His work includes the stereoselective and total synthesis of bioactive natural products, such as antitumor polyketides like Callystatin and Ratjadone, as well as studies on isocoumarins, dihydroisocoumarins, and their nitrogen and sulfur analogues. Dr. Bhatti has also contributed to the synthesis, biological evaluation, heterocyclization, QSAR studies, and computational investigations of acyl thioureas.

In addition, his research explores the design, synthesis, and bioevaluation of novel nitrogen-sulfur heterocycles and bisheterocycles using hybrid pharmacophore approaches. His work extends into organic electronic materials, including carbazole, fluorene, and perylene-based compounds for OLEDs, as well as fluorescent dyes like Rylene, Rylene azo-hybrids, porphyrins, xanthenes, anthocyanins, and triarylmethane derivatives.

Dr. Bhatti has advanced green chemistry through methodologies such as one-pot multi-component reactions, microwave-assisted synthesis, aqueous synthesis, and mechanochemical synthesis. His discoveries include several small and hybrid molecules with potent enzyme inhibitory properties, as well as novel drugs targeting multidrug-resistant Gram-negative pathogens, with a focus on structure-transport relationships. Additionally, his work in bioimaging has contributed to the development of in vivo cancer probes, ion sensors, materials with aggregate-induced emission properties, and components for dye-sensitized solar cells (DSSCs).

This revision improves clarity and readability while maintaining all key details.

  • Synthetic Bioorganic and Medicinal Chemistry; Natural Products, Heterocyclic Chemistry
  • Stereoselective/ total synthesis of bioactive Natural Products; Antitumor Polyketides: Callystatin, Ratjadone; Isocoumarins, Dihydroisocoumarins and their nitrogen, sulfur analogues.
  • Acyl thioureas: Synthesis, biological evaluation, heterocyclization, QSAR, vibrational, DFT studies of diverse
  • Design, Synthesis bioevaluation, chemo-informatics, binding analysis, Molecular docking, pharmacokinetics of Novel Nitrogen Sulphur heterocycles, bisheterocycles; Isochromanyl and coumarinyl heterocycles using hybrid pharmacophore approach.
  • Carbazole, Fluorene and Perylene Based Materials for Organic Electronic Applications OLEDs
  • Synthesis and absorption, emission, and electrochemical studies of Flourescent and other dyes: new Rylene and Rylene azo-hybrid, Porphyrin, Xanthene, Anthocyanin, Triarylmethane; Aggregate Induced Emission
  • One pot Multi Component Reactions, Microwave Assisted Synthesis, Aqueous Synthesis, Mechanochemical Synthesis as a apart of environment friendly Green Chemistry.
  • Discovered several small & hybrid molecules as Enzyme Inhibitors many folds more potent than the standard drugs.
  • Development of novel drugs against MDR Gram-negative pathogens and investigation of structure-transport relationships
  • In vivo Cancer probes for bio imaging, Ions sensors, AIE materials, DSSC materials

Academic career

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Positions held

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Dr. Aamer Saeed Bhatti held various positions throughout his career, including various teaching and research positions at different institutions, along with the corresponding dates:

  1. Prof. Dr. Aamer Saeed Bhatti is currently serving as the Dean of Natural Sciences at Quaid-i-Azam University, in addition to his distinguished role as a scholar and former Chairperson of the Department of Chemistry.
  2. He served as a Professor (TTS-21) at Quaid-i-Azam University in Islamabad from December 11, 2012, to an unspecified end date (presently holding this position).
  3. Prior to that, they were an Associate Professor (BPS-20) at the same university from May 31, 2008, until December 11, 2012.
  4. The position of Assistant Professor* (BPS-19) was also held at Quaid-i-Azam University from August 10, 2002, to May 31, 2008.
  5. He held the role of Associate Professor (BPS-19) at G.C. University in Lahore from October 1, 2001, to August 9, 2002.
  6. An Alexander von Humboldt Post-doctoral fellowship was completed at Hannover University in Germany from August 2, 2000, to September 30, 2001.
  7. The individual returned to G.C. University in Lahore as an Associate Professor (BPS-19) from October 1, 2001, to August 9, 2002, which overlaps with point 4 and may indicate a clerical error or a return to the same position.
  8. He was an Associate Professor* (BPS-19) at Govt. Post Graduate College in Rabwah (Chenab Nagar), Faisalabad from May 29, 1999, to August 1, 2000.
  9. He worked as an Assistant Professor (BPS-18) at Govt. Degree College on G.T. Road, Jhelum from December 21, 1994, to May 28, 1999.
  10. The career started as a Lecturer (BPS-17) at Federal Govt. Boys College in Sihala, Islamabad, from October 15, 1990, to December 20, 1994.
  11. Selected by FPSC as Lecturer for Islamabad Colleges & first Govt. service joined on 15-10-1990.
  12. Selected directly as Assistant Professor (1994) and Associate Professor (1998) by PPSC.
  13. Sacrificed the Associate Professorship and joined the Quaid-I-Azam University, Islamabad as Assistant Professor due to profound interest in research. Total Teaching/ Research Experience: ca 32 Years

Scholarships, honors and awards

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  • Alexander von Humboldt scholarship for German language Course, Goethe Institute Göttingen, Germany.
  • Alexander von Humboldt, Post-Doctoral Fellowship Germany.
  • Recipient of Research Productivity Allowance 2004-2011 and Research Productivity Allowance (2011-2018) Category A, by Pakistan Council for Science and Technology (PCST).
  • Innovation Award, (Invention to Innovation Summit March 19-20, 2015), Punjab University Lahore
  • Working on University-Industry Research cooperation program (IRP) of HEC

Fellowships

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  • Fellow Royal Society of Chemistry (2022)
  • Fellow of the Chemical Society of Pakistan.
  • Member Royal Society of Chemistry (2022)
  • The Chemical Society of Pakistan (lifetime).
  • American Association for Advancement of Science (AAAS)
  • Humboldt Forum & German Alumni Forum Islamabad, Pakistan
  • Member, Curriculum Committee, National Testing Service Pakistan

Selected Publications, Chapters, and Books.

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References

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  1. ^ "Prof. Dr. Aamer Saeed Bhatti". chem.qau.edu.pk. Retrieved 2024-08-26.
  2. ^ "Tamgha-e-Imtiaz", Wikipedia, 2024-08-23, retrieved 2024-09-06
  3. ^ "Home". chem.qau.edu.pk. Retrieved 2024-08-26.
  4. ^ "QAU – Islamabad, Pakistan". Retrieved 2024-08-26.
  5. ^ "Home". chem.qau.edu.pk. Retrieved 2024-05-24.
  6. ^ "Home". chemicalsocietyofpakistan.com. Retrieved 2024-08-26.
  7. ^ "Pakistan Academy of Sciences | Fellow Profile". www.paspk.org. Retrieved 2024-08-26.
  8. ^ our.correspondent (2020-11-22). "81 Pakistanis among world's top 2% scientists". The Express Tribune. Retrieved 2024-09-06. {{cite web}}: |last= has generic name (help)
  9. ^ Ioannidis, John P. A.; Boyack, Kevin W.; Baas, Jeroen (2020-10-16). "Updated science-wide author databases of standardized citation indicators". PLOS Biology. 18 (10): e3000918. doi:10.1371/journal.pbio.3000918. ISSN 1545-7885.{{cite journal}}: CS1 maint: unflagged free DOI (link)