{{Infobox road
|country=US
|type=I
|route=60
|map=
|length_mi=3392 miles
|length_ref=
|length_round=2
|established=1926
|direction_a=West
|direction_b=East
|terminus_a=
US 27 / US 42 / US 52 / US 127 / SR 3 / SR 264 in Cincinnati, OH
|junction=
I-76 / Penna Turnpike in Monroeville, PA
|terminus_b=
I-95
