 The Center for Regenerative Therapies Dresden from outside. | |
| Established | 2006 |
|---|---|
Field of research | Bioengineering |
| Faculty | Center for Molecular and Cellular Bioengineering |
| Location | Dresden, Germany 51°3′23.3″N 13°46′33.48″E / 51.056472°N 13.7759667°E |
| Affiliations | TU Dresden |
| Website | https://tu-dresden.de/cmcb/crtd |
| Map | |
  Location in Germany  Blufisch1234/sandbox/subpage2 (Saxony) | |
The Center for Regenerative Therapies Dresden (CRTD) is a biomedical research center located in Dresden, Germany. It is part of the scientific unit Center for Molecular and Cellular Bioengineering (CMCB) of the Technische Universität Dresden. The research at the CRTD concentrates on the principles of cell and tissue regeneration. By gaining a deeper understanding of regenerative processes, the CRTD researchers intend to establish a basis for new diagnostics and therapies for human diseases. Therefore, the connection between basic research and clinical practice plays an important role at the CRTD.
Location
editThe CRTD building is located in Dresden-Johannstadt in the vicinity of the Biotechnology Center (BIOTEC), the B CUBE - Center for Molecular Bioengineering, and the Universitätsklinikum Carl Gustav Carus Dresden.
History
editThe CRTD was founded in 2006 as the first German Research Foundation (DFG) Research Center in eastern Germany and was awarded the status of Cluster of Excellence.[1][2]The CRTD was funded by the DFG until 2019 and during that time it received around 60 million euro.
Construction of CRTD building was approved in July 2007.[3] The foundation stone was laid on August 21, 2009.[4] The building designed by Gunter Henn was opened in October 2011.[4][5] It is located next to the University Hospital Carl Gustav Carus Dresden and the BioInnovationsZentrum (also BioInnovationCenter).
In 2016, the CRTD together with the BIOTEC and the B CUBE - Center for Molecular Bioengineering became part of the Center for Molecular and Cellular Bioengineering (CMCB) - a newly founded central scientific unit of the TU Dresden.[6][7] In 2019, the TU Dresden together with the Free State of Saxony took over the CRTD funding. It is now co-funded by the TU Dresden and the Faculty of Medicine Carl Gustav Carus.[8]
Since the CRTD was founded, the research group leaders raised 75.6 million euro in third-party funding (including a flat-rate programme fee) until 2021. This included well-known funding formats such as Collaborative Research Centres (SFBs), Alexander von Humboldt Professorships, ERC Starting Grants, ERC Advanced Grants,ERC Proof-of-Concept Grant, Freigeist Fellowships, and Emmy Noether Grants.[8][9]
Research
editThe CRTD hosts more than 20 research groups.[10] Many of its groups are co-affiliated with other institutes in Dresden or Saxony: the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), the Max Planck Institute for Physics of Complex Systems (MPI-PKS), the Helmholtz-Zentrums Dresden-Rossendorf, the German Center for Neurodegenerative Diseases (DZNE), and the University Hospital Carl Gustav Carus Dresden among others.
The research at the CRTD focuses on a fundamental understanding of stem cell biology and tissue regeneration. This understanding can help develop new models for human diseases as well as novel diagnostics and therapies.
Declared mission of the CRTD is to discover principles of cell and tissue regeneration, and to leverage these principles for recognition, treatment, and reversal of diseases. Thus, the link of basic research to the clinic plays an important role at the CRTD.[11]
The CRTD research groups focus on four different research areas:[12]
- Hematology and immunology - regulation of the immune system with focus on the formation of blood and immune cells. The emphasis here lies on the development of therapies for immune diseases
- Diabetes – investigation of how the destruction of β-cells by immune cells can be prevented and how β-cells can be used for therapies
- Neurodegenerative diseases - the mechanisms of proliferation and differentiation of brain stem cells
- Bone and tissue regeneration – with a goal of discovering the mechanisms of regeneration in the musculoskeletal system as well as understanding the interactions with immune and cancer cells
The CRTD hosts two Alexander von Humboldt Professors: Prof. Catherina Becker and Prof. Michael Sieweke.[12]
Teaching
editAs part of the Center for Molecular and Cellular Bioengineering (CMCB), a central scientific unit of the TU Dresden, the CRTD is involved in teaching in the Bachelor program Molecular Biology and Biotechnology as well as in the Master’s programs offered by the CMCB: Regenerative Biology and Medicine as well as Molecular Bioengineering and Physics of Life (formerly Nanobiophysics).[13]
It is also possible to complete a PhD at the CRTD, either in the Dresden International Graduate School for Biomedicine and Bioengineering (DIGS-BB) or as Bioscience PhD Student (BiPS).[13]
Furthermore, the CRTD offers positions for volunteers in the context of the “Freiwilliges Soziales Jahr” in cooperation with the German Red Cross of Saxony.[14]
Facilities
editThe CRTD uses and contributes to the Technology Platform of the Center for Molecular and Cellular Bioengineering (CMCB) which offers facilities and services in the field of Life Science to all scientists at the TU Dresden and cooperating institutes.[15]
Cooperations & Partners
editThe CRTD cooperates with a variety of partner organizations, including the University Hospital Carl Gustav Carus Dresden, the Max Planck Institute of Molecular Cell Biology and Genetics, the Leibniz Institute for Polymer Research, and the German Center for Neurodegenerative Diseases (DZNE).[8]
References
edit- ^ "CRTD - Zentrum für Regenerative Therapien TU Dresden". Dresden. Retrieved 19 April 2022.
- ^ "Excellence Initiative at a Glance" (PDF). Deutsche Forschungsgemeinschaft (DFG). Retrieved 19 April 2022.
- ^ "CRTD - Center for Regenerative Therapies Dresden Laborgebäude" (PDF). Staatsbetrieb Immobilien- und Baumanagement Sachsen. Retrieved 19 April 2022.
- ^ a b "Grundsteinlegung für neues Forschungszentrum der Deutschen Forschungsgemeinschaft an der Technischen Universität Dresden". Sächsisches Staatsministerium für Wissenschaft, Kultur und Tourismus. Retrieved 19 April 2022.
- ^ "Opening of research center for regenerative therapies (CRTD) in Dresden". KREBS+KIEFER. Retrieved 19 April 2022.
- ^ "About CMCB". Center for Molecular and Cellular Bioengineering. Retrieved 19 April 2022.
- ^ "Zeit für Veränderungen". Innovation & Strukturwandel. Federal Ministry of Education and Research. Retrieved 19 April 2022.
- ^ a b c "Financing". Center for Regenerative Therapies Dresden. Center for Regenerative Therapies Dresden (CRTD). Retrieved 19 April 2022.
- ^ "ERC Proof of Concept Grant for Prof. Michael Sieweke". TU Dresden. TU Dresden. Retrieved 5 May 2022.
- ^ "Research Groups". Center for Regenerative Therapies Dresden. CRTD. Retrieved 19 April 2022.
- ^ "Mission". Center for Regenerative Therapies Dresden. CRTD. Retrieved 19 April 2022.
- ^ a b "Research Groups at the CRTD". Center for Regenerative Therapies Dresden. CRTD. Retrieved 19 April 2022.
- ^ a b "Education & Career". Center for Regenerative Therapies Dresden (CRTD). Center for Regenerative Therapies Dresden (CRTD). Retrieved 20 April 2022.
- ^ "Freiwilliges Soziales Jahr im Wissenschaftlichen Bereich" (PDF). Center for Regenerative Therapies Dresden (CRTD). Center for Regenerative Therapies Dresden (CRTD). Retrieved 20 April 2022.
- ^ "Technology Platform". Center for Regenerative Therapies Dresden (CRTD). Center for Regenerative Therapies Dresden (CRTD). Retrieved 20 April 2022.
External links
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