Hemoglobin A1c levels in Diabetes
editProtein type | metalloproteinglobulin |
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Function | oxygen-transport |
Hemoglobin A1c levels vary within a patient, from a healthy patient to a patient that has diabetes. Testings are done to see the blood sugar level of a patient with diabetes over the past 3 months.[1] Due to the patients having diabetes, their blood sugar levels are higher than a normal patient, enabling them to have a high percentage of A1c. When testing a patient, the sought out levels of A1c is below 5.7%. Between 5.7% and 6.4% would be pre-diabetes, whereas any percent at or above 6.5% is the corresponding levels for patients with diabetes[2]. When looking for the percentage of A1c and as the percentage increased, the higher the blood sugar level is, indicating that it is dangerous to remain in that state.
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· Hemoglobin
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Hemoglobin
editAs a human body contains many proteins, hemoglobin is a protein that carries oxygen in the red blood cells to the organs and tissues. While it carries oxygen, it also transports carbon dioxide from the organs and tissues back to the lungs.[3] When hemoglobin levels are too low, it could be caused from iron deficiency, which prevents the production of hemoglobin.
Hemoglobins are made of four main components, two which are alpha-globulin chains and two beta-globulin chains. Each chain contains a heme. The hemes on the chains contain an Iron atom allows for transportation of oxygen and carbon dioxide[4]. Because of this, it grants the ability to give the color red from the iron being transported.
Glycated Hemoglobin
editA1c is a type of hemoglobin that binds to glucose, where is it formed from the interactions between rede blood cells and sugars within the blood. When it becomes sugar attaches to blood, it becomes glycated hemoglobin[5], also known as A1c. The amount of A1c determines their average blood sugar levels, over the past 3 months as that is the life span of a red blood cell[6].
Levels of Hemoglobin A1c
editHbA1c level is dependent on the amount of glucose present. The higher the glucose levels, there will be more A1c produced as the hemoglobin binds to the glucose. Over 2-3 months of measurement, if the average blood sugar is below 5.7%, then a patient is healthy and continue the diet they are on. If the average blood sugar is 6.5% or higher, they could be classified to be diabetic. In the case of someone with diabetes, the ideal range for them is 7%[7]. If over the past 2-3 months, the average blood sugar is between the two amounts, <5.7% < X < 6.5%, then there is the possibility that the patient may be diagnosed with being prediabetic. For someone who is already has diabetes, knowing the levels of A1c will help keep the glucose levels under watch[8]. With the levels of sugar being monitored by someone with diabetes, the ideal blood sugar level is below 140, where the lowest safe blood sugar level is 70 mg/dL[9].
HbA1C | Diagnosis |
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<5.7% | Normal |
5.7-6.4% | Prediabetes |
>6.5% | Diabetes |
estimated Average Glucose (eAG)
according to A1c[11] | |
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IF A1C % IS: | YOUR EAG IS: |
6 | 126 |
6.5 | 140 |
7 | 154 |
7.5 | 169 |
8 | 183 |
8.5 | 197 |
9 | 212 |
9.5 | 226 |
10 | 240 |
10.5 | 255 |
11 | 269 |
11.5 | 283 |
12 | 298 |
Symptoms
editSymptoms from having high blood sugar levels may consist of the following[12]:
- increased thirst
- headaches
- blurred vision
- fatigue
- weight loss
Symptoms from having low blood sugar levels may consist of the following[13]:
- shaking
- weakness
- headaches
- constant sweating
- feeling anxious
Under extreme circumstances, symptoms for having low or high blood sugar levels consist of the following[14]:
- fainting
- seizure
References
edit- ^ "Diabetes Tests & Diagnosis | NIDDK". National Institute of Diabetes and Digestive and Kidney Diseases. Retrieved 2020-11-15.
- ^ "Diagnosis | ADA". www.diabetes.org. Retrieved 2020-11-15.
- ^ "Hemoglobin test - Mayo Clinic". www.mayoclinic.org. Retrieved 2020-11-15.
- ^ "Hemoglobin: Normal, High, Low Levels, Causes & Symptoms". MedicineNet. Retrieved 2020-11-17.
- ^ "What is a glycated hemoglobin test (HbA1c)?". WebMD. Retrieved 2020-11-15.
- ^ "Hemoglobin A1C (HbA1c) Test: MedlinePlus Medical Test". medlineplus.gov. Retrieved 2020-11-17.
- ^ "What is a glycated hemoglobin test (HbA1c)?". WebMD. Retrieved 2020-11-15.
- ^ "Hemoglobin A1C (HbA1c) Test: MedlinePlus Medical Test". medlineplus.gov. Retrieved 2020-11-17.
- ^ "Low blood sugar - self-care: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 2020-11-17.
- ^ "Diagnosis | ADA". www.diabetes.org. Retrieved 2020-11-15.
- ^ "A1c Test - Blood Sugar & Estimated Avg Glucose Chart | Kaiser Permanente Washington". wa.kaiserpermanente.org. Retrieved 2020-11-17.
- ^ "Hyperglycemia and Diabetes". WebMD. Retrieved 2020-11-17.
- ^ "Low blood sugar - self-care: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 2020-11-17.
- ^ "Low blood sugar - self-care: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 2020-11-17.