Date | Time | Opponent | Rank | Site | TV | Result | Attendance |
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08/30/2003 | 12:10 pm | Central Michigan* | No. 4 | | ESPN | W 45-7 | 110,637 |
09/06/2003 | 12:00 pm | Houston* | No. 5 | - Michigan Stadium
- Ann Arbor, MI
| ESPN | W 50-3 | 109,580 |
09/13/2003 | 3:30 pm | No. 15 Notre Dame* | No. 5 | - Michigan Stadium
- Ann Arbor, MI
| ABC | W 38-0 | 111,726 |
09/20/2003 | 12:30 pm | at No. 22 Oregon* | No. 3 | | ABC | L 31-27 | 59,023 |
09/27/2003 | 12:10 pm | Indiana | No. 11 | - Michigan Stadium
- Ann Arbor, MI
| ESPN | W 31-17 | 110,788 |
10/04/2003 | 2:30 pm | at No. 23 Iowa | No. 9 | | ABC | L 30-27 | 70,397 |
10/10/2003 | 7:00 pm | at No. 17 Minnesota | No. 20 | | ESPN | W 38-35 | 62,374 |
10/18/2003 | 12:00 pm | Illinois | No. 20 | - Michigan Stadium
- Ann Arbor, MI
| ESPN | W 56-14 | 110,231 |
10/25/2003 | 3:30 pm | No. 10 Purdue Boilermakers | No. 13 | - Michigan Stadium
- Ann Arbor, MI
| ABC | W 31-3 | 111,349 |
11/01/2003 | 12:00 pm | at No. 9 Michigan State | No. 11 | | ABC | W 27-20 | 75,129 |
11/15/2003 | 2:30 pm | at Northwestern | No. 5 | | ESPN | W 41-10 | 40,681 |
11/22/2003 | 12:00 pm | No. 4 Ohio State | No. 5 | - Michigan Stadium
- Ann Arbor, MI
| ABC | W 35-21 | 112,118 |
01/01/2004 | 2:00 pm | vs. No. 1 USC* | No. 4 | | ABC | L 28-14 | 93,849 |
- *Non-conference game
- Homecoming
- Rankings from AP / Coaches Polls released prior to game
- All times are in Eastern time
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