Wikipedia

User:Macularcarotenoids/Professor john nolan

Professor John Nolan
File:John Nolan 2018.jpg
Born(1980-08-15)15 August 1980
Carrick on Suir, Tipperary, Ireland
NationalityIrish
OccupationAcademic Principal Investigator
Known formacular pigment, age-related macular degeneration, meso-zeaxanthin, lutein, zeaxanthin, cognitive function
Academic background
EducationWaterford Institute of Technology, Medical College of Georgia

Professor John Nolan was born and raised in the Republic of Ireland. John Nolan studied Science at Waterford Institute of Technology (WIT). It was there where he obtained his primary degree. He also completed his PhD at WIT. Following this, John worked at the Medical College of Georgia in the US as part of his Fulbright Scholarship. Upon successful completion of his Fulbright Scholarship, John returned to Waterford, where he established the Macular Pigment Research Group. This group of scientists have spent 18 years studying the role of nutrition for the eye, with some key discoveries. In 2011, John won the prestigious European Research Council Starting Grant where he conducted the Central Retinal Enrichment Supplementation Trials (CREST). This work essentially confirms the scientific discovery that the use of meso-zeaxanthin, in conjunction with lutein and zeaxanthin (the three nutritional pigments that are found at the back of the eye), can enhance vision in healthy subjects and in patients with early age-related macular degeneration (the leading cause of blindness in the western world). In 2016, John founded the Nutrition Research Centre Ireland, which is a multidisciplinary group studying the role of nutrition and lifestyle for human well-being. Their current research interests include the study of key nutrients for cognitive function and brain health with a major goal of identifying ways to reduce risk of Alzheimer’s disease.

Early life and education

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John was born in 1980 and was raised in Carrick-on-Suir, Co. Tipperary. John completed his leaving cert in the CBS Secondary School in Carrick-on-Suir and went on to complete his Bachelor of Science (BSc) in Applied Biology with Quality Management in Waterford Institute of Technology (WIT), Ireland. In 2002, following the completion of his degree, John went on to pursue a PhD in the WIT with a thesis entitled "Determinants of macular pigment in healthy subjects". From 2005-2006 John won the prestigious Irish/American Fulbright Scholarship for Science, where he relocated to the Medical College of Georgia to pursue his project entitled "Spatial profile of macular pigment and its relationship with foveal architecture". In 2006 John returned to Waterford Institute of Technology where he founded the Macular Pigment Research Group.

Academic Profile

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Research into Macular Degeneration and Carotenoids

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Research into Cognitive Function and Carotenoids

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University of San Diego, California

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References

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[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]

  1. ^ Akuffo, Kwadwo Owusu; Beatty, Stephen; Peto, Tunde; Stack, Jim; Stringham, Jim; Kelly, David; Leung, Irene; Corcoran, Laura; Nolan, John M. (10 01, 2017). "The Impact of Supplemental Antioxidants on Visual Function in Nonadvanced Age-Related Macular Degeneration: A Head-to-Head Randomized Clinical Trial". Investigative Ophthalmology & Visual Science. 58 (12): 5347–5360. doi:10.1167/iovs.16-21192. ISSN 1552-5783. PMID 29053808. {{cite journal}}: Check date values in: |date= (help)
  2. ^ Phelan, David; Prado-Cabrero, Alfonso; Nolan, John M. (2018-02-03). "Analysis of Lutein, Zeaxanthin, and Meso-Zeaxanthin in the Organs of Carotenoid-Supplemented Chickens". Foods. 7 (2): 20. doi:10.3390/foods7020020. PMC 5848124. PMID 29401639.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
  3. ^ Power, Rebecca; Coen, Robert F.; Beatty, Stephen; Mulcahy, Riona; Moran, Rachel; Stack, Jim; Howard, Alan N.; Nolan, John M. (2018-01-09). "Supplemental Retinal Carotenoids Enhance Memory in Healthy Individuals with Low Levels of Macular Pigment in A Randomized, Double-Blind, Placebo-Controlled Clinical Trial". Journal of Alzheimer's Disease. 61 (3): 947–961. doi:10.3233/jad-170713. ISSN 1387-2877.
  4. ^ Moran, Rachel; Beatty, Stephen; Stack, Jim; O'Halloran, Aisling M.; Feeney, Joanne; Akuffo, Kwadwo O.; Peto, Tunde; Kenny, Rose Anne; Nolan, John M. (March 2018). "The Relationship Between Plasma Concentrations of Lutein and Zeaxanthin with Self-Reported and Actual Prevalence of AMD in an Irish Population-Based Sample". Current Eye Research. 43 (3): 383–390. doi:10.1080/02713683.2017.1403633. ISSN 1460-2202. PMID 29172786.
  5. ^ Feeney, Joanne; O'Leary, Neil; Moran, Rachel; O'Halloran, Aisling M.; Nolan, John M.; Beatty, Stephen; Young, Ian S.; Kenny, Rose Anne (2017-10-01). "Plasma Lutein and Zeaxanthin Are Associated With Better Cognitive Function Across Multiple Domains in a Large Population-Based Sample of Older Adults: Findings from The Irish Longitudinal Study on Aging". The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 72 (10): 1431–1436. doi:10.1093/gerona/glw330. ISSN 1758-535X. PMID 28329221.
  6. ^ Moran, R.; Nolan, J. M.; Stack, J.; O'Halloran, A. M.; Feeney, J.; Akuffo, K. O.; Kenny, R. A.; Beatty, S. (2017). "Non-Dietary Correlates and Determinants of Plasma Lutein and Zeaxanthin Concentrations in the Irish Population". The Journal of Nutrition, Health & Aging. 21 (3): 254–261. doi:10.1007/s12603-016-0729-7. ISSN 1760-4788. PMID 28244563.
  7. ^ Kelly, David; Nolan, John M.; Howard, Alan N.; Stack, Jim; Akuffo, Kwadwo O.; Moran, Rachel; Thurnham, David I.; Dennison, Jessica; Meagher, Katherine A. (01 2017). "Serum and macular response to carotenoid-enriched egg supplementation in human subjects: the Egg Xanthophyll Intervention clinical Trial (EXIT)". The British Journal of Nutrition. 117 (1): 108–123. doi:10.1017/S0007114516003895. ISSN 1475-2662. PMC 5297582. PMID 28122649. {{cite journal}}: Check date values in: |date= (help)CS1 maint: PMC format (link)
  8. ^ Nolan, John M.; Power, Rebecca; Stringham, Jim; Dennison, Jessica; Stack, Jim; Kelly, David; Moran, Rachel; Akuffo, Kwadwo O.; Corcoran, Laura (2016-06-01). "Enrichment of Macular Pigment Enhances Contrast Sensitivity in Subjects Free of Retinal Disease: Central Retinal Enrichment Supplementation Trials - Report 1". Investigative Ophthalmology & Visual Science. 57 (7): 3429–3439. doi:10.1167/iovs.16-19520. ISSN 1552-5783. PMID 27367585.
  9. ^ Akuffo, Kwadwo Owusu; Nolan, John M.; Peto, Tunde; Stack, Jim; Leung, Irene; Corcoran, Laura; Beatty, Stephen (02 2017). "Relationship between macular pigment and visual function in subjects with early age-related macular degeneration". The British Journal of Ophthalmology. 101 (2): 190–197. doi:10.1136/bjophthalmol-2016-308418. ISSN 1468-2079. PMC 5293853. PMID 27091854. {{cite journal}}: Check date values in: |date= (help)CS1 maint: PMC format (link)
  10. ^ Nolan, John M.; Meagher, Katherine A.; Howard, Alan N.; Moran, Rachel; Thurnham, David I.; Beatty, Stephen (2016). "Lutein, zeaxanthin and meso-zeaxanthin content of eggs laid by hens supplemented with free and esterified xanthophylls". Journal of Nutritional Science. 5: e1. doi:10.1017/jns.2015.35. ISSN 2048-6790. PMC 4709836. PMID 26793307.{{cite journal}}: CS1 maint: PMC format (link)
  11. ^ Bernstein, Paul S.; Li, Binxing; Vachali, Preejith P.; Gorusupudi, Aruna; Shyam, Rajalekshmy; Henriksen, Bradley S.; Nolan, John M. (January 2016). "Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease". Progress in Retinal and Eye Research. 50: 34–66. doi:10.1016/j.preteyeres.2015.10.003. ISSN 1873-1635. PMC 4698241. PMID 26541886.{{cite journal}}: CS1 maint: PMC format (link)
  12. ^ Kelly, David; Coen, Robert F.; Akuffo, Kwadwo Owusu; Beatty, Stephen; Dennison, Jessica; Moran, Rachel; Stack, Jim; Howard, Alan N.; Mulcahy, Riona (2015). "Cognitive Function and Its Relationship with Macular Pigment Optical Density and Serum Concentrations of its Constituent Carotenoids". Journal of Alzheimer's disease: JAD. 48 (1): 261–277. doi:10.3233/JAD-150199. ISSN 1875-8908. PMC 4923753. PMID 26401946.{{cite journal}}: CS1 maint: PMC format (link)
  13. ^ Akuffo, K. O.; Nolan, J. M.; Howard, A. N.; Moran, R.; Stack, J.; Klein, R.; Klein, B. E.; Meuer, S. M.; Sabour-Pickett, S. (July 2015). "Sustained supplementation and monitored response with differing carotenoid formulations in early age-related macular degeneration". Eye (London, England). 29 (7): 902–912. doi:10.1038/eye.2015.64. ISSN 1476-5454. PMC 4506345. PMID 25976647.{{cite journal}}: CS1 maint: PMC format (link)
  14. ^ Nolan, John M.; Loskutova, Ekaterina; Howard, Alan; Mulcahy, Riona; Moran, Rachel; Stack, Jim; Bolger, Maggie; Coen, Robert F.; Dennison, Jessica (2015). "The impact of supplemental macular carotenoids in Alzheimer's disease: a randomized clinical trial". Journal of Alzheimer's disease: JAD. 44 (4): 1157–1169. doi:10.3233/JAD-142265. ISSN 1875-8908. PMID 25408222.
  15. ^ Thurnham, David I.; Nolan, John M.; Howard, Alan N.; Beatty, Stephen (August 2015). "Macular response to supplementation with differing xanthophyll formulations in subjects with and without age-related macular degeneration". Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. 253 (8): 1231–1243. doi:10.1007/s00417-014-2811-3. ISSN 1435-702X. PMID 25311651.
  16. ^ Nolan, John M.; Loskutova, Ekaterina; Howard, Alan N.; Moran, Rachel; Mulcahy, Riona; Stack, Jim; Bolger, Maggie; Dennison, Jessica; Akuffo, Kwadwo Owusu (2014). "Macular pigment, visual function, and macular disease among subjects with Alzheimer's disease: an exploratory study". Journal of Alzheimer's disease: JAD. 42 (4): 1191–1202. doi:10.3233/JAD-140507. ISSN 1875-8908. PMID 25024317.
  17. ^ Sabour-Pickett, Sarah; Beatty, Stephen; Connolly, Eithne; Loughman, James; Stack, Jim; Howard, Alan; Klein, Ronald; Klein, Barbara E.; Meuer, Stacy M. (September 2014). "Supplementation with three different macular carotenoid formulations in patients with early age-related macular degeneration". Retina (Philadelphia, Pa.). 34 (9): 1757–1766. doi:10.1097/IAE.0000000000000174. ISSN 1539-2864. PMID 24887490.
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