Clinical data | |
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Trade names | Baciim |
AHFS/Drugs.com | Systemic: Monograph Topical: Monograph Eye: Monograph |
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Routes of administration | Topical, intramuscular |
Drug class | Antibiotic |
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Identifiers | |
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Chemical and physical data | |
Formula | C66H103N17O16S |
Molar mass | 1422.71 g·mol−1 |
3D model (JSmol) | |
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Bacitracin is an antibiotic.[3] When applied to the skin, it is used to treat superficial bacterial skin infections.[2] When applied to the eyes, it is used to treat bacterial conjunctivitis.[1] It has also been used by mouth to treat Clostridioides difficile diarrhea, but is not a preferred treatment.[3]
Common side effects when applied to the skin or eyes include irritation and rash.[2] Other side effects may include allergic reactions.[2] When given by injected kidney problems may occur.[3] Safety in pregnancy is unclear.[2] It works by interfering with the building of a cell wall.[1]
Bacitracin was first isolated in 1945 and approved for medical use in the United States in 1948.[4][3] It is available as a generic medication.[5] In the United States a 3.5 gram tube for use in the eyes costs about 31 USD as of 2022.[5] It was isolated form Bacillus licheniformis.[4] It is also available in combination with other medications.[2]
References
edit- ^ a b c "Bacitracin (EENT) Monograph for Professionals". Drugs.com. Archived from the original on 16 July 2017. Retrieved 8 January 2022.
- ^ a b c d e f g "Bacitracin (Topical) Monograph for Professionals". Drugs.com. Archived from the original on 8 December 2021. Retrieved 8 January 2022.
- ^ a b c d e "Bacitracin Monograph for Professionals". Drugs.com. Archived from the original on 25 February 2021. Retrieved 7 January 2022.
- ^ a b Hahn, Fred E. (6 December 2012). Mechanism of Action of Antibacterial Agents. Springer Science & Business Media. p. 1. ISBN 978-3-642-46403-4. Archived from the original on 11 January 2022. Retrieved 7 January 2022.
- ^ a b "Bacitracin Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 12 October 2016. Retrieved 7 January 2022.