User:Mr. Ibrahem/Fenoprofen

Mr. Ibrahem/Fenoprofen
Clinical data
Trade names	Nalfon, others
AHFS/Drugs.com	Monograph
MedlinePlus	a681026
Pregnancy; category	C;
Routes of; administration	By mouth
Drug class	Nonsteroidal anti-inflammatory drug (NSAID)
Legal status
Legal status	UK: POM (Prescription only); US: ℞-only;
Pharmacokinetic data
Metabolism	Major urinary metabolites are fenoprofen glucuronide and 4′-hydroxyfenoprofen glucuronide.
Onset of action	Within 30 min
Elimination half-life	3 hours
Duration of action	Up to 6 hrs
Excretion	Kidney (~90%)
Identifiers
	IUPAC name 2-(3-phenoxyphenyl)propanoic acid;
Chemical and physical data
Formula	C15H14O3
Molar mass	242.274 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(O)C(c2cc(Oc1ccccc1)ccc2)C;
	InChI InChI=1S/C15H14O3/c1-11(15(16)17)12-6-5-9-14(10-12)18-13-7-3-2-4-8-13/h2-11H,1H3,(H,16,17) ; Key:RDJGLLICXDHJDY-UHFFFAOYSA-N ;
	(verify)

Fenoprofen, sold under the brand name Nalfon among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain and inflammation.^[1] This may include in rheumatoid arthritis, gout, and osteoarthritis.^[1] It is taken by mouth.^[1] Onsets is within 30 minutes and last up to 6 hours.^[1]

Common side effects include heart burn, nausea, headache, dizziness, anxiety, and swelling.^[1] Other side effects may include liver problems, Stevens-Johnson syndrome, anaphylaxis, kidney problems, heart failure, stomach bleeding, heart attack, and high blood pressure.^[1] Use in the later part of pregnancy may harm the baby.^[1] It works by blocking COX1 and COX2.^[1]

Fenoprofen was approved for medical use in the United States in 1976.^[1] It is available as a generic medication.^[2] In the United States 30 tablets of 600 mg cost about 30 USD as of 2021.^[2] It is not available in the United Kingdom as of 2021.^[3]

References

^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o "Fenoprofen Monograph for Professionals". Drugs.com. Archived from the original on 20 January 2021. Retrieved 10 December 2021.
^ ^a ^b "Fenoprofen Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 10 December 2021.
^ "Fenoprofen tablets for pain and inflammation". patient.info. Archived from the original on 19 October 2021. Retrieved 10 December 2021.

[AHFS2021-1] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o "Fenoprofen Monograph for Professionals". Drugs.com. Archived from the original on 20 January 2021. Retrieved 10 December 2021.

[GX2021-2] "Fenoprofen Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 10 December 2021.

[3] "Fenoprofen tablets for pain and inflammation". patient.info. Archived from the original on 19 October 2021. Retrieved 10 December 2021.

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