Clinical data | |||
---|---|---|---|
Pronunciation | zal-a-plon | ||
Trade names | Sonata, Starnoc, Andante, others | ||
AHFS/Drugs.com | Monograph | ||
MedlinePlus | a601251 | ||
Routes of administration | By mouth (medical), intranasal (recreational) | ||
Drug class | Z drug[1] | ||
Legal status | |||
Legal status |
| ||
Pharmacokinetic data | |||
Bioavailability | 30% (by mouth) | ||
Metabolism | Liver | ||
Elimination half-life | 1–1.5 h | ||
Excretion | Kidney | ||
Identifiers | |||
| |||
Chemical and physical data | |||
Formula | C17H15N5O | ||
Molar mass | 305.341 g·mol−1 | ||
3D model (JSmol) | |||
| |||
| |||
(verify) |
Zaleplon, sold under the brand names Sonata among others, is a medication used to treat trouble sleeping.[2] Use is not recommended for more than two weeks.[2][4] It is taken by mouth.[2]
Common side effects include headache, dizziness, and abdominal pain.[2] Serious side effects can include sleepwalking or other complex sleep behavior, aggression, anaphylaxis, and abuse.[2] Use is not recommended in those with significant liver problems.[2] Safety in pregnancy and breastfeeding is unclear and such use is not recommended.[3] It is a nonbenzodiazepine hypnotic from the pyrazolopyrimidine class.[2]
Zaleplon was approved for medical use in the United States in 1999.[2] In the United States it costs about 13 USD per month as of 2021.[5] It is not currently sold in Canada and is no longer approved in the United Kingdom.[6][1]
References
edit- ^ a b "Sleeping pills". www.mind.org.uk. Archived from the original on 2021-02-26. Retrieved 2021-08-04.
- ^ a b c d e f g h i j k "Zaleplon Monograph for Professionals". Drugs.com. Archived from the original on 17 April 2021. Retrieved 4 August 2021.
- ^ a b "Zaleplon (Sonata) Use During Pregnancy". Drugs.com. Archived from the original on 18 April 2021. Retrieved 4 August 2021.
- ^ "Zaleplon" (PDF). Archived (PDF) from the original on 29 August 2021. Retrieved 4 August 2021.
- ^ "Zaleplon Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 17 May 2020. Retrieved 4 August 2021.
- ^ "Authorized Sleep-Aid Medications in Canada". www.healthycanadians.gc.ca. Archived from the original on 9 November 2017. Retrieved 4 August 2021.