Peer Review Comments 9/19/2016
The first "Corrections/Ideas" section can be more concise. All of the smaller changes that could be made didn't necessarily need to be added. Also, to help conciseness you could use this section to correct one particular section instead of the entire article. The information you put in this section is very helpful for the author to see and are useful for overall clarification of the article.
For the "additions" section I think the sources are good and relevant. One of them is a little out-of-date (the one labeled as performed in 1999). I thought I remembered the experiments had to be done after 2000, but Dr. Munger would be the most useful person to ask. Also, when speaking to Dr. Munger about how to add sources, she requested there be information about the method of the experiments. That could help with clarity and relatedness. Overall good job!
Working Memory and Diseases
A functional issue with the working memory is the cause of many memory issues that are seen in diseases. Without extensive research done on working memory, much information we have about diseases would also be lost. The decrease of working memory function is normally seen in neural diseases:
Parkinson's Disease[1]: Patients with Parkinson's show signs of a reduced verbal function of working memory. They wanted to find if the reduction is due to a lack of ability to focus on relevant tasks, or a low amount of memory capacity. Twenty-one patients with Parkinson's were tested in comparison to the control group of 28 participants of the same age.The researchers found that both hypotheses were the reason working memory function is reduced which did not fully agree with their hypothesis that it is either one or the other.[2]
Alzheimers Disease[3]: As Alzheimer's Disease becomes more serious, less working memory functions. There is one study that focuses on the neural connections and fluidity of working memory in mice brains. Half of the mice were given an injection that is similar to Alzheimer's effects, and the other half were not. Then they were expected to go through a maze that is a task to test working memory. The study help answer questions about how Alzheimers can deteriorate the working memory and ultimately obliterate memory functions.[4]
Huntington's Disease[5]: A group of researchers hosted a study that researched the function and connectivity of working memory over a 30-month longitudinal experiment. It found that there were certain places in the brain where most connectivity was decreased in pre-huntington diseased patients, in comparison to the control group that remained consistently functional.[6]
- ^ "Parkinson's disease". Wikipedia. September 23, 2016.
- ^ Lee, Eun-Young (August 5, 2010). "Visual working memory deficits in patients with Parkinson's disease are due to both reduced storage capacity and impaired ability to filter out irrelevant information". Retrieved September 7, 2016.
- ^ "Alzheimer's Disease". Wikipedia. September 23, 2016.
- ^ Tiaotiao, Liu (Dec. 2014). "Functional connectivity in a rat model of Alzheimer's disease during a working memory task". Current Alzheimers Research. 11(10). PMID 25387338. Retrieved September 15, 2016.
{{cite journal}}: Check date values in:|date=(help) - ^ "Huntington's Disease". September 22, 2016.
- ^ Poudel, Govinda R. (January 2015). "Functional changes during working memory in Huntington's disease: 30-month longitudinal data from the IMAGE-HD study". Brain Structure and Function. 220.