What is the difference in the addiction to smoking and chewing tobacco? The addiction to smoking and chewing tobacco differs primarily in the method of nicotine delivery and the substances involved. Smoking delivers nicotine rapidly to the bloodstream through inhalation, leading to a quicker onset of addiction. In contrast, chewing tobacco provides a slower release of nicotine as it is absorbed through the mucous membranes in the mouth, resulting in a different pattern of use and addiction. Both forms, however, lead to dependence due to the nicotine content and can cause significant health risks. For more insights into tobacco products and their effects, visit NashaBar.