Mechanism Alkaline Phosphatase release
editSkeletal
editSerum alkaline phosphatase is acquired through several sources: liver, bone, kidney, intestine, and placenta (for women). Skeletal alkaline phosphatase, on the other hand, is localised in osteoblasts and extracellular layers of newly synthesized matrix. However, the mechanism of which skeletal alkaline phosphatase is released into circulation is yet unclear.