Lipid Metabolism (improving article): My additions are in BOLD.
Lipid metabolism is the synthesis and degradation of lipids in cells.
Lipid metabolism is the break down or storage of fats for energy; these fats are obtained from consuming food and absorbing them or they are synthesized by an animal's liver. The majority of lipids found in the human body from ingesting food are Triglycerides, also known as fats.[1] Since lipids are fats, lipid metabolism is often considered the digestion and absorption processes of dietary fats. Break down of lipids in the body begins in the mouth through chemical digestion. Lipids then continue to the stomach where chemical digestion continues, and mechanical digestion begins (Peristalsis). The majority of lipid digestion and absorption, however, occurs once the fats reach the small intestines. Chemicals from both the pancreas and liver are transported to the small intestines to help breakdown the fats[2], along with further mechanical digestion, until they are able to be absorbed into the small intestines. Lipid metabolism does exist in plants, though the processes differ in some ways when compared to animals. Lipogenesis is the process of synthesizing these fats. Lipid metabolism often begins with hydrolysis, which occurs when a chemical breaks down as a reaction to coming in contact with water. Since lipids (fats) are hydrophobic, hydrolysis in lipid metabolism occurs in the cytoplasm which ends up creating glycerol and fatty acids. Due to the hydrophobic nature of lipids they require special transport proteins known as lipoproteins, which are hydrophilic. Lipoproteins are categorized by their density levels. The varying densities between the types of lipoproteins are characteristic to what type of fats they transport. A number of these lipoproteins are synthesized in the liver, but not all of them originate from this organ.
Lipid metabolism disorders are illnesses where trouble occurs in breaking down or synthesizing fats (or fat-like substances). A good deal of the time these disorders are hereditary, meaning it's a condition that is passed along from parent to child through their genes. Gaucher's disease (Type I, Type II, and Type III), Niemann–Pick disease, Tay–Sachs disease, and Fabry's disease are all diseases where those afflicted can have a disorder of their body's lipid metabolism. Rarer diseases concerning a disorder of the lipid metabolism are sitosterolemia, Wolman's Disease, Refsum's disease, and cerebrotendinous xanthomatosis.
The types of lipids involved in Lipid Metabolism include:
- Bile salts
- Cholesterols
- Eicosanoids
- Glycolipids
- Ketone bodies
- Fatty acids - see also fatty acid metabolism
- Phospholipids
- Sphingolipids
- Steroid - see also steroidogenesis
- Triacylglycerols (fats) - see also lipolysis and lipogenesis
Article Evaluation: Side Chain[3]
- Although the article does a decent job of presenting factual background information, the article would be enhanced through the use of examples.
- Good information in the founder of the concept of "side chains."
- Basic information given on the use of side chains in proteins and in biochemistry.
- More examples and further information would better describe the purpose of side chains.
Article Evaluation: Mandelian Inheritance[4]
- Information and facts on the page are derived from a diverse selection of creditable sources.
- Non-biased information is presented, and the facts are presented neutrally without the purpose of persuading the reader.
- Mendel's Laws are summarized in order to give the reader a better understanding of this model of genetics.
- This is a good representation of a well written and well sited Wikipedia page focused on genetics .
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- ^ Baynes, Dominiczak (2014). Medical Biochemistry. Saunders, Elsevier Limited. pp. 121–122. ISBN 978-1-4557-4580-7.
- ^ W., Pelley, John (2012). Elsevier's integrated review. Biochemistry. Pelley, John W. (2nd ed ed.). Philadelphia: Elsevier/Saunders. ISBN 9780323074469. OCLC 773586101.
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has extra text (help)CS1 maint: multiple names: authors list (link) - ^ "Side chain". Wikipedia. 2017-01-26.
- ^ "Mendelian inheritance". Wikipedia. 2017-08-30.