Paulaosu

Paula Ordonez

I worked at Kagoshima University on the evaluation of uracil derivatives as novel HIV-1 inhibitors ^[1] ^[2]. I currently work as research scientist on the HIV-1 restriction factor SAMHD1 at the National Institute for Medical Research, website.

HIV-1 virion

HIV-1 assembling at the surface of an infected macrophage

Catalytic core of human SAMHD1

^ Isono, Y; Sakakibara, N; Ordonez, P; Hamasaki, T; Baba, M; Ikejiri, M; Maruyama, T (7 October 2011). "Synthesis of 1-benzyl-3-(3,5-dimethylbenzyl)uracil derivatives with potential anti-HIV activity". Antiviral chemistry & chemotherapy. 22 (2): 57–65. PMID 21984685.
^ Ordonez, P; Hamasaki, T; Isono, Y; Sakakibara, N; Ikejiri, M; Maruyama, T; Baba, M (May 2012). "Anti-human immunodeficiency virus type 1 activity of novel 6-substituted 1-benzyl-3-(3,5-dimethylbenzyl)uracil derivatives". Antimicrobial agents and chemotherapy. 56 (5): 2581–9. PMID 22290950.