- INFO: Beginning work on GPR157... {November 26, 2007 2:31:22 PM PST}
- CREATE: Found no pages, creating new page. {November 26, 2007 2:31:43 PM PST}
- CREATED: Created new protein page: GPR157 {November 26, 2007 2:31:50 PM PST}
- INFO: Beginning work on OR10W1... {November 26, 2007 2:42:29 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:43:10 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 10, subfamily W, member 1
| HGNCid = 15139
| Symbol = OR10W1
| AltSymbols =; OR10W1P; OR10W1Q; OR11-236; UNQ6469
| OMIM =
| ECnumber =
| Homologene = 79418
| MGIid = 3031324
| GeneAtlas_image1 = PBB_GE_OR10W1_gnf1h02104_s_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81341
| Hs_Ensembl = ENSG00000172772
| Hs_RefseqProtein = NP_997257
| Hs_RefseqmRNA = NM_207374
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 57790989
| Hs_GenLoc_end = 57791906
| Hs_Uniprot = Q8NGF6
| Mm_EntrezGene = 258098
| Mm_Ensembl = ENSMUSG00000061387
| Mm_RefseqmRNA = NM_001011832
| Mm_RefseqProtein = NP_001011832
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 19
| Mm_GenLoc_start = 13721465
| Mm_GenLoc_end = 13722415
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 10, subfamily W, member 1''', also known as '''OR10W1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR10W1 olfactory receptor, family 10, subfamily W, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81341| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR10W1 olfactory receptor, family 10, subfamily W, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81341| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Clark HF, Gurney AL, Abaya E, ''et al.'' |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265-70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR11H1... {November 26, 2007 2:34:50 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:35:09 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 11, subfamily H, member 1
| HGNCid = 15404
| Symbol = OR11H1
| AltSymbols =; OR22-1
| OMIM =
| ECnumber =
| Homologene = 84609
| MGIid =
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81061
| Hs_Ensembl = ENSG00000196143
| Hs_RefseqProtein = NP_001005239
| Hs_RefseqmRNA = NM_001005239
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 14
| Hs_GenLoc_start = 18447594
| Hs_GenLoc_end = 18448574
| Hs_Uniprot =
| Mm_EntrezGene =
| Mm_Ensembl =
| Mm_RefseqmRNA =
| Mm_RefseqProtein =
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 11, subfamily H, member 1''', also known as '''OR11H1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR11H1 olfactory receptor, family 11, subfamily H, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81061| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR11H1 olfactory receptor, family 11, subfamily H, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81061| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR2AE1... {November 26, 2007 2:43:10 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:43:46 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 2, subfamily AE, member 1
| HGNCid = 15087
| Symbol = OR2AE1
| AltSymbols =; OR2AE2
| OMIM =
| ECnumber =
| Homologene = 79678
| MGIid = 3030004
| GeneAtlas_image1 = PBB_GE_OR2AE1_gnf1h11267_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81392
| Hs_Ensembl = ENSG00000176607
| Hs_RefseqProtein = NP_001005276
| Hs_RefseqmRNA = NM_001005276
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 7
| Hs_GenLoc_start = 99311621
| Hs_GenLoc_end = 99312592
| Hs_Uniprot = Q8NHA4
| Mm_EntrezGene = 258959
| Mm_Ensembl = ENSMUSG00000062245
| Mm_RefseqmRNA = NM_146957
| Mm_RefseqProtein = NP_667168
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 16
| Mm_GenLoc_start = 19519288
| Mm_GenLoc_end = 19520229
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 2, subfamily AE, member 1''', also known as '''OR2AE1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2AE1 olfactory receptor, family 2, subfamily AE, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81392| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR2AE1 olfactory receptor, family 2, subfamily AE, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81392| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author= |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097-108 |year= 1999 |pmid= 9847074 |doi= }}
*{{cite journal | author=Thompson EE, Kuttab-Boulos H, Yang L, ''et al.'' |title=Sequence diversity and haplotype structure at the human CYP3A cluster. |journal=Pharmacogenomics J. |volume=6 |issue= 2 |pages= 105-14 |year= 2006 |pmid= 16314882 |doi= 10.1038/sj.tpj.6500347 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR2C3... {November 26, 2007 2:47:09 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:47:54 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 2, subfamily C, member 3
| HGNCid = 15005
| Symbol = OR2C3
| AltSymbols =; OR2C4; OR2C5P; OST742
| OMIM =
| ECnumber =
| Homologene = 64884
| MGIid = 3031204
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81472
| Hs_Ensembl = ENSG00000196242
| Hs_RefseqProtein = NP_932340
| Hs_RefseqmRNA = NM_198074
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 1
| Hs_GenLoc_start = 245760057
| Hs_GenLoc_end = 245763764
| Hs_Uniprot = Q8N628
| Mm_EntrezGene = 258528
| Mm_Ensembl = ENSMUSG00000042869
| Mm_RefseqmRNA = NM_146535
| Mm_RefseqProtein = NP_666746
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 13
| Mm_GenLoc_start = 21079814
| Mm_GenLoc_end = 21080764
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 2, subfamily C, member 3''', also known as '''OR2C3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2C3 olfactory receptor, family 2, subfamily C, member 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81472| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR2C3 olfactory receptor, family 2, subfamily C, member 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81472| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR2G2... {November 26, 2007 2:45:43 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:47:09 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 2, subfamily G, member 2
| HGNCid = 15007
| Symbol = OR2G2
| AltSymbols =; OR1-32
| OMIM =
| ECnumber =
| Homologene = 84572
| MGIid = 2177506
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81470
| Hs_Ensembl = ENSG00000177489
| Hs_RefseqProtein = NP_001001915
| Hs_RefseqmRNA = NM_001001915
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 1
| Hs_GenLoc_start = 245818285
| Hs_GenLoc_end = 245819238
| Hs_Uniprot = Q8NGZ5
| Mm_EntrezGene = 258623
| Mm_Ensembl = ENSMUSG00000045202
| Mm_RefseqmRNA = NM_146630
| Mm_RefseqProtein = NP_666841
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 17
| Mm_GenLoc_start = 37403499
| Mm_GenLoc_end = 37404428
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 2, subfamily G, member 2''', also known as '''OR2G2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2G2 olfactory receptor, family 2, subfamily G, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81470| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR2G2 olfactory receptor, family 2, subfamily G, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81470| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR2G3... {November 26, 2007 2:44:52 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:45:43 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 2, subfamily G, member 3
| HGNCid = 15008
| Symbol = OR2G3
| AltSymbols =; OR1-33
| OMIM =
| ECnumber =
| Homologene = 88396
| MGIid = 2177500
| GeneAtlas_image1 = PBB_GE_OR2G3_gnf1h10914_at_tn.png
| GeneAtlas_image2 = PBB_GE_OR2G3_gnf1h10915_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81469
| Hs_Ensembl = ENSG00000177476
| Hs_RefseqProtein = NP_001001914
| Hs_RefseqmRNA = NM_001001914
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 1
| Hs_GenLoc_start = 245835511
| Hs_GenLoc_end = 245836440
| Hs_Uniprot = Q8NGZ4
| Mm_EntrezGene = 258263
| Mm_Ensembl = ENSMUSG00000062337
| Mm_RefseqmRNA = NM_207155
| Mm_RefseqProtein = NP_997038
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 17
| Mm_GenLoc_start = 37267431
| Mm_GenLoc_end = 37268384
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 2, subfamily G, member 3''', also known as '''OR2G3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2G3 olfactory receptor, family 2, subfamily G, member 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81469| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR2G3 olfactory receptor, family 2, subfamily G, member 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81469| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR2L5... {November 26, 2007 2:44:36 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:44:52 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 2, subfamily L, member 5
| HGNCid = 15011
| Symbol = OR2L5
| AltSymbols =; OR2L11; OR2L5P
| OMIM =
| ECnumber =
| Homologene =
| MGIid =
| Function =
| Component =
| Process =
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81466
| Hs_Ensembl =
| Hs_RefseqProtein =
| Hs_RefseqmRNA =
| Hs_GenLoc_db =
| Hs_GenLoc_chr =
| Hs_GenLoc_start =
| Hs_GenLoc_end =
| Hs_Uniprot =
| Mm_EntrezGene =
| Mm_Ensembl =
| Mm_RefseqmRNA =
| Mm_RefseqProtein =
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 2, subfamily L, member 5''', also known as '''OR2L5''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2L5 olfactory receptor, family 2, subfamily L, member 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81466| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR2L5 olfactory receptor, family 2, subfamily L, member 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81466| accessdate = }}</ref>
}}
==References==
{{reflist}}
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR4A15... {November 26, 2007 2:42:06 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:42:29 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 4, subfamily A, member 15
| HGNCid = 15152
| Symbol = OR4A15
| AltSymbols =; OR11-118
| OMIM =
| ECnumber =
| Homologene = 74244
| MGIid = 3031068
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81328
| Hs_Ensembl = ENSG00000181958
| Hs_RefseqProtein = NP_001005275
| Hs_RefseqmRNA = NM_001005275
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 54891936
| Hs_GenLoc_end = 54892970
| Hs_Uniprot = Q8NGL6
| Mm_EntrezGene = 258975
| Mm_Ensembl = ENSMUSG00000075090
| Mm_RefseqmRNA = NM_146973
| Mm_RefseqProtein = NP_667184
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 2
| Mm_GenLoc_start = 89163322
| Mm_GenLoc_end = 89164266
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 4, subfamily A, member 15''', also known as '''OR4A15''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR4A15 olfactory receptor, family 4, subfamily A, member 15| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81328| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR4A15 olfactory receptor, family 4, subfamily A, member 15| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81328| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR4A16... {November 26, 2007 2:41:42 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:42:06 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 4, subfamily A, member 16
| HGNCid = 15153
| Symbol = OR4A16
| AltSymbols =; OR11-117; OR4A16Q
| OMIM =
| ECnumber =
| Homologene = 45045
| MGIid = 3031074
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81327
| Hs_Ensembl = ENSG00000181961
| Hs_RefseqProtein = NP_001005274
| Hs_RefseqmRNA = NM_001005274
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 54867253
| Hs_GenLoc_end = 54868239
| Hs_Uniprot = Q8NH70
| Mm_EntrezGene = 258804
| Mm_Ensembl = ENSMUSG00000075087
| Mm_RefseqmRNA = NM_146808
| Mm_RefseqProtein = NP_667019
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 2
| Mm_GenLoc_start = 89240172
| Mm_GenLoc_end = 89241116
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 4, subfamily A, member 16''', also known as '''OR4A16''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR4A16 olfactory receptor, family 4, subfamily A, member 16| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81327| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR4A16 olfactory receptor, family 4, subfamily A, member 16| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81327| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR4A5... {November 26, 2007 2:41:11 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:41:42 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 4, subfamily A, member 5
| HGNCid = 15162
| Symbol = OR4A5
| AltSymbols =; OR11-111
| OMIM =
| ECnumber =
| Homologene = 45077
| MGIid = 3031081
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81318
| Hs_Ensembl = ENSG00000176529
| Hs_RefseqProtein = NP_001005272
| Hs_RefseqmRNA = NM_001005272
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 51268024
| Hs_GenLoc_end = 51268971
| Hs_Uniprot = Q8NH83
| Mm_EntrezGene = 258968
| Mm_Ensembl = ENSMUSG00000075081
| Mm_RefseqmRNA = NM_146966
| Mm_RefseqProtein = NP_667177
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 2
| Mm_GenLoc_start = 89409995
| Mm_GenLoc_end = 89410939
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 4, subfamily A, member 5''', also known as '''OR4A5''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR4A5 olfactory receptor, family 4, subfamily A, member 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81318| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR4A5 olfactory receptor, family 4, subfamily A, member 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81318| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Taylor TD, Noguchi H, Totoki Y, ''et al.'' |title=Human chromosome 11 DNA sequence and analysis including novel gene identification. |journal=Nature |volume=440 |issue= 7083 |pages= 497-500 |year= 2006 |pmid= 16554811 |doi= 10.1038/nature04632 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR4C15... {November 26, 2007 2:40:52 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:41:11 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 4, subfamily C, member 15
| HGNCid = 15171
| Symbol = OR4C15
| AltSymbols =; OR11-127; OR11-134
| OMIM =
| ECnumber =
| Homologene = 81548
| MGIid = 3031045
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81309
| Hs_Ensembl = ENSG00000181939
| Hs_RefseqProtein = NP_001001920
| Hs_RefseqmRNA = NM_001001920
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 55078359
| Hs_GenLoc_end = 55079471
| Hs_Uniprot = Q8NGM1
| Mm_EntrezGene = 258025
| Mm_Ensembl = ENSMUSG00000075112
| Mm_RefseqmRNA = NM_001011804
| Mm_RefseqProtein = NP_001011804
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 2
| Mm_GenLoc_start = 88730217
| Mm_GenLoc_end = 88731152
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 4, subfamily C, member 15''', also known as '''OR4C15''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR4C15 olfactory receptor, family 4, subfamily C, member 15| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81309| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR4C15 olfactory receptor, family 4, subfamily C, member 15| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81309| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR4F4... {November 26, 2007 2:30:24 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:31:07 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 4, subfamily F, member 4
| HGNCid = 8301
| Symbol = OR4F4
| AltSymbols =; OLA-7501; OR4F18; OR4F11P; OR4F19
| OMIM =
| ECnumber =
| Homologene = 88410
| MGIid =
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 26682
| Hs_Ensembl = ENSG00000186092
| Hs_RefseqProtein = NP_001004195
| Hs_RefseqmRNA = NM_001004195
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 15
| Hs_GenLoc_start = 100279868
| Hs_GenLoc_end = 100280785
| Hs_Uniprot = Q96R69
| Mm_EntrezGene = 623583
| Mm_Ensembl =
| Mm_RefseqmRNA = XM_888068
| Mm_RefseqProtein = XP_893161
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 4, subfamily F, member 4''', also known as '''OR4F4''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR4F4 olfactory receptor, family 4, subfamily F, member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26682| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR4F4 olfactory receptor, family 4, subfamily F, member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26682| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Trask BJ, Friedman C, Martin-Gallardo A, ''et al.'' |title=Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes. |journal=Hum. Mol. Genet. |volume=7 |issue= 1 |pages= 13-26 |year= 1998 |pmid= 9384599 |doi= }}
*{{cite journal | author=Mefford HC, Linardopoulou E, Coil D, ''et al.'' |title=Comparative sequencing of a multicopy subtelomeric region containing olfactory receptor genes reveals multiple interactions between non-homologous chromosomes. |journal=Hum. Mol. Genet. |volume=10 |issue= 21 |pages= 2363-72 |year= 2002 |pmid= 11689483 |doi= }}
*{{cite journal | author=Linardopoulou E, Mefford HC, Nguyen O, ''et al.'' |title=Transcriptional activity of multiple copies of a subtelomerically located olfactory receptor gene that is polymorphic in number and location. |journal=Hum. Mol. Genet. |volume=10 |issue= 21 |pages= 2373-83 |year= 2002 |pmid= 11689484 |doi= }}
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR4K15... {November 26, 2007 2:35:09 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:35:28 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 4, subfamily K, member 15
| HGNCid = 15353
| Symbol = OR4K15
| AltSymbols =; OR14-20; OR4K15Q
| OMIM =
| ECnumber =
| Homologene = 84571
| MGIid = 3030561
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81127
| Hs_Ensembl = ENSG00000169488
| Hs_RefseqProtein = NP_001005486
| Hs_RefseqmRNA = NM_001005486
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 14
| Hs_GenLoc_start = 19513518
| Hs_GenLoc_end = 19514564
| Hs_Uniprot = Q8NH41
| Mm_EntrezGene = 258316
| Mm_Ensembl = ENSMUSG00000059488
| Mm_RefseqmRNA = NM_146319
| Mm_RefseqProtein = NP_666431
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 14
| Mm_GenLoc_start = 49048530
| Mm_GenLoc_end = 49049504
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 4, subfamily K, member 15''', also known as '''OR4K15''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR4K15 olfactory receptor, family 4, subfamily K, member 15| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81127| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR4K15 olfactory receptor, family 4, subfamily K, member 15| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81127| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR4P4... {November 26, 2007 2:40:34 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:40:52 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 4, subfamily P, member 4
| HGNCid = 15180
| Symbol = OR4P4
| AltSymbols =; OR4P3P
| OMIM =
| ECnumber =
| Homologene = 84576
| MGIid =
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81300
| Hs_Ensembl = ENSG00000181927
| Hs_RefseqProtein = NP_001004124
| Hs_RefseqmRNA = NM_001004124
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 55162410
| Hs_GenLoc_end = 55163348
| Hs_Uniprot = Q8NGL7
| Mm_EntrezGene =
| Mm_Ensembl =
| Mm_RefseqmRNA =
| Mm_RefseqProtein =
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 4, subfamily P, member 4''', also known as '''OR4P4''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR4P4 olfactory receptor, family 4, subfamily P, member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81300| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR4P4 olfactory receptor, family 4, subfamily P, member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81300| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR51E2... {November 26, 2007 2:39:47 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:40:34 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 51, subfamily E, member 2
| HGNCid = 15195
| Symbol = OR51E2
| AltSymbols =; OR51E3P; OR52A2; PSGR
| OMIM =
| ECnumber =
| Homologene = 23713
| MGIid = 2157548
| GeneAtlas_image1 = PBB_GE_OR51E2_221424_s_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81285
| Hs_Ensembl = ENSG00000167332
| Hs_RefseqProtein = NP_110401
| Hs_RefseqmRNA = NM_030774
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 4657977
| Hs_GenLoc_end = 4675648
| Hs_Uniprot = Q9H255
| Mm_EntrezGene = 170639
| Mm_Ensembl = ENSMUSG00000043366
| Mm_RefseqmRNA = NM_130866
| Mm_RefseqProtein = NP_570936
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 7
| Mm_GenLoc_start = 102614552
| Mm_GenLoc_end = 102633216
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 51, subfamily E, member 2''', also known as '''OR51E2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR51E2 olfactory receptor, family 51, subfamily E, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81285| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR51E2 olfactory receptor, family 51, subfamily E, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81285| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Adams MD, Kerlavage AR, Fleischmann RD, ''et al.'' |title=Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. |journal=Nature |volume=377 |issue= 6547 Suppl |pages= 3-174 |year= 1995 |pmid= 7566098 |doi= }}
*{{cite journal | author=Xu LL, Stackhouse BG, Florence K, ''et al.'' |title=PSGR, a novel prostate-specific gene with homology to a G protein-coupled receptor, is overexpressed in prostate cancer. |journal=Cancer Res. |volume=60 |issue= 23 |pages= 6568-72 |year= 2001 |pmid= 11118034 |doi= }}
*{{cite journal | author=Xia C, Ma W, Wang F, ''et al.'' |title=Identification of a prostate-specific G-protein coupled receptor in prostate cancer. |journal=Oncogene |volume=20 |issue= 41 |pages= 5903-7 |year= 2001 |pmid= 11593396 |doi= 10.1038/sj.onc.1204803 }}
*{{cite journal | author=Yuan TT, Toy P, McClary JA, ''et al.'' |title=Cloning and genetic characterization of an evolutionarily conserved human olfactory receptor that is differentially expressed across species. |journal=Gene |volume=278 |issue= 1-2 |pages= 41-51 |year= 2002 |pmid= 11707321 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Weng J, Wang J, Cai Y, ''et al.'' |title=Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers. |journal=Int. J. Cancer |volume=113 |issue= 5 |pages= 811-8 |year= 2005 |pmid= 15499628 |doi= 10.1002/ijc.20635 }}
*{{cite journal | author=Weng J, Ma W, Mitchell D, ''et al.'' |title=Regulation of human prostate-specific G-protein coupled receptor, PSGR, by two distinct promoters and growth factors. |journal=J. Cell. Biochem. |volume=96 |issue= 5 |pages= 1034-48 |year= 2006 |pmid= 16149059 |doi= 10.1002/jcb.20600 }}
*{{cite journal | author=Xu LL, Sun C, Petrovics G, ''et al.'' |title=Quantitative expression profile of PSGR in prostate cancer. |journal=Prostate Cancer Prostatic Dis. |volume=9 |issue= 1 |pages= 56-61 |year= 2006 |pmid= 16231015 |doi= 10.1038/sj.pcan.4500836 }}
*{{cite journal | author=Wang J, Weng J, Cai Y, ''et al.'' |title=The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase. |journal=Prostate |volume=66 |issue= 8 |pages= 847-57 |year= 2006 |pmid= 16491480 |doi= 10.1002/pros.20389 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR51G2... {November 26, 2007 2:36:01 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:39:47 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 51, subfamily G, member 2
| HGNCid = 15198
| Symbol = OR51G2
| AltSymbols =; OR11-28
| OMIM =
| ECnumber =
| Homologene = 64962
| MGIid = 3030411
| GeneAtlas_image1 = PBB_GE_OR51G2_gnf1h11097_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81282
| Hs_Ensembl = ENSG00000176893
| Hs_RefseqProtein = NP_001005238
| Hs_RefseqmRNA = NM_001005238
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 4892525
| Hs_GenLoc_end = 4893469
| Hs_Uniprot = Q8NGK0
| Mm_EntrezGene = 259113
| Mm_Ensembl = ENSMUSG00000043354
| Mm_RefseqmRNA = NM_147109
| Mm_RefseqProtein = NP_667320
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 7
| Mm_GenLoc_start = 102846873
| Mm_GenLoc_end = 102847811
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 51, subfamily G, member 2''', also known as '''OR51G2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR51G2 olfactory receptor, family 51, subfamily G, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81282| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR51G2 olfactory receptor, family 51, subfamily G, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81282| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Gilad Y, Bustamante CD, Lancet D, Pääbo S |title=Natural selection on the olfactory receptor gene family in humans and chimpanzees. |journal=Am. J. Hum. Genet. |volume=73 |issue= 3 |pages= 489-501 |year= 2003 |pmid= 12908129 |doi= 10.1086/378132 }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR5AC2... {November 26, 2007 2:34:31 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:34:50 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 5, subfamily AC, member 2
| HGNCid = 15431
| Symbol = OR5AC2
| AltSymbols =; HSA1
| OMIM =
| ECnumber =
| Homologene = 51800
| MGIid = 3030032
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81050
| Hs_Ensembl = ENSG00000196578
| Hs_RefseqProtein = NP_473447
| Hs_RefseqmRNA = NM_054106
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 3
| Hs_GenLoc_start = 99288707
| Hs_GenLoc_end = 99289636
| Hs_Uniprot = Q9NZP5
| Mm_EntrezGene = 258036
| Mm_Ensembl = ENSMUSG00000052537
| Mm_RefseqmRNA = NM_001011808
| Mm_RefseqProtein = NP_001011808
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 16
| Mm_GenLoc_start = 59143760
| Mm_GenLoc_end = 59144680
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 5, subfamily AC, member 2''', also known as '''OR5AC2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR5AC2 olfactory receptor, family 5, subfamily AC, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81050| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR5AC2 olfactory receptor, family 5, subfamily AC, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81050| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Rouquier S, Blancher A, Giorgi D |title=The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 6 |pages= 2870-4 |year= 2000 |pmid= 10706615 |doi= 10.1073/pnas.040580197 }}
*{{cite journal | author=Muzny DM, Scherer SE, Kaul R, ''et al.'' |title=The DNA sequence, annotation and analysis of human chromosome 3. |journal=Nature |volume=440 |issue= 7088 |pages= 1194-8 |year= 2006 |pmid= 16641997 |doi= 10.1038/nature04728 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR6J1... {November 26, 2007 2:31:07 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:31:22 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 6, subfamily J, member 1
| HGNCid = 14707
| Symbol = OR6J1
| AltSymbols =; OR6J1P; OR6J2
| OMIM =
| ECnumber =
| Homologene =
| MGIid =
| Function =
| Component =
| Process =
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 79549
| Hs_Ensembl =
| Hs_RefseqProtein =
| Hs_RefseqmRNA =
| Hs_GenLoc_db =
| Hs_GenLoc_chr =
| Hs_GenLoc_start =
| Hs_GenLoc_end =
| Hs_Uniprot =
| Mm_EntrezGene =
| Mm_Ensembl =
| Mm_RefseqmRNA =
| Mm_RefseqProtein =
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 6, subfamily J, member 1''', also known as '''OR6J1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR6J1 olfactory receptor, family 6, subfamily J, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79549| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR6J1 olfactory receptor, family 6, subfamily J, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79549| accessdate = }}</ref>
}}
==References==
{{reflist}}
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR6K2... {November 26, 2007 2:44:02 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:44:36 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 6, subfamily K, member 2
| HGNCid = 15029
| Symbol = OR6K2
| AltSymbols =; OR1-17
| OMIM =
| ECnumber =
| Homologene = 17185
| MGIid = 3030254
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81448
| Hs_Ensembl = ENSG00000196171
| Hs_RefseqProtein = NP_001005279
| Hs_RefseqmRNA = NM_001005279
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 1
| Hs_GenLoc_start = 156936092
| Hs_GenLoc_end = 156937066
| Hs_Uniprot = Q8NGY2
| Mm_EntrezGene = 258302
| Mm_Ensembl = ENSMUSG00000055033
| Mm_RefseqmRNA = NM_146305
| Mm_RefseqProtein = NP_666417
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 1
| Mm_GenLoc_start = 175995450
| Mm_GenLoc_end = 175996415
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 6, subfamily K, member 2''', also known as '''OR6K2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR6K2 olfactory receptor, family 6, subfamily K, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81448| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR6K2 olfactory receptor, family 6, subfamily K, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81448| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR6N2... {November 26, 2007 2:43:46 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:44:02 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 6, subfamily N, member 2
| HGNCid = 15035
| Symbol = OR6N2
| AltSymbols =; OR1-23
| OMIM =
| ECnumber =
| Homologene = 17362
| MGIid = 3030264
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81442
| Hs_Ensembl = ENSG00000188340
| Hs_RefseqProtein = NP_001005278
| Hs_RefseqmRNA = NM_001005278
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 1
| Hs_GenLoc_start = 157013096
| Hs_GenLoc_end = 157014049
| Hs_Uniprot = Q8NGY6
| Mm_EntrezGene = 258713
| Mm_Ensembl =
| Mm_RefseqmRNA = NM_146718
| Mm_RefseqProtein = NP_666929
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 6, subfamily N, member 2''', also known as '''OR6N2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR6N2 olfactory receptor, family 6, subfamily N, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81442| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR6N2 olfactory receptor, family 6, subfamily N, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81442| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on OR8J3... {November 26, 2007 2:35:28 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:36:01 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Olfactory receptor, family 8, subfamily J, member 3
| HGNCid = 15312
| Symbol = OR8J3
| AltSymbols =; OR11-173
| OMIM =
| ECnumber =
| Homologene = 84596
| MGIid = 3030896
| GeneAtlas_image1 = PBB_GE_OR8J3_gnf1h10850_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 81168
| Hs_Ensembl = ENSG00000167822
| Hs_RefseqProtein = NP_001004064
| Hs_RefseqmRNA = NM_001004064
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 55660823
| Hs_GenLoc_end = 55661770
| Hs_Uniprot = Q8NGG0
| Mm_EntrezGene = 259082
| Mm_Ensembl =
| Mm_RefseqmRNA = NM_147078
| Mm_RefseqProtein = NP_667289
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Olfactory receptor, family 8, subfamily J, member 3''', also known as '''OR8J3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR8J3 olfactory receptor, family 8, subfamily J, member 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81168| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text =
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Fuchs T, Malecova B, Linhart C, ''et al.'' |title=DEFOG: a practical scheme for deciphering families of genes. |journal=Genomics |volume=80 |issue= 3 |pages= 295-302 |year= 2003 |pmid= 12213199 |doi= }}
*{{cite journal | author=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584-9 |year= 2004 |pmid= 14983052 |doi= }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on TAS1R1... {November 26, 2007 2:33:55 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:34:31 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Taste receptor, type 1, member 1
| HGNCid = 14448
| Symbol = TAS1R1
| AltSymbols =; TR1; GPR70; T1R1; gm148
| OMIM = 606225
| ECnumber =
| Homologene = 12888
| MGIid = 1927505
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0008067 |text = metabotropic glutamate, GABA-B-like receptor activity}} {{GNF_GO|id=GO:0008527 |text = taste receptor activity}} {{GNF_GO|id=GO:0046982 |text = protein heterodimerization activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}} {{GNF_GO|id=GO:0050917 |text = sensory perception of umami taste}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 80835
| Hs_Ensembl = ENSG00000173662
| Hs_RefseqProtein = NP_619642
| Hs_RefseqmRNA = NM_138697
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 1
| Hs_GenLoc_start = 6537828
| Hs_GenLoc_end = 6562404
| Hs_Uniprot = Q7RTX1
| Mm_EntrezGene = 110326
| Mm_Ensembl = ENSMUSG00000028950
| Mm_RefseqmRNA = NM_031867
| Mm_RefseqProtein = NP_114073
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 4
| Mm_GenLoc_start = 150871714
| Mm_GenLoc_end = 150882368
| Mm_Uniprot = Q3U5H1
}}
}}
'''Taste receptor, type 1, member 1''', also known as '''TAS1R1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TAS1R1 taste receptor, type 1, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80835| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding several different isoforms have been found for this gene.<ref name="entrez">{{cite web | title = Entrez Gene: TAS1R1 taste receptor, type 1, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80835| accessdate = }}</ref>
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Chandrashekar J, Hoon MA, Ryba NJ, Zuker CS |title=The receptors and cells for mammalian taste. |journal=Nature |volume=444 |issue= 7117 |pages= 288-94 |year= 2007 |pmid= 17108952 |doi= 10.1038/nature05401 }}
*{{cite journal | author=Hoon MA, Adler E, Lindemeier J, ''et al.'' |title=Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity. |journal=Cell |volume=96 |issue= 4 |pages= 541-51 |year= 1999 |pmid= 10052456 |doi= }}
*{{cite journal | author=Makalowska I, Sood R, Faruque MU, ''et al.'' |title=Identification of six novel genes by experimental validation of GeneMachine predicted genes. |journal=Gene |volume=284 |issue= 1-2 |pages= 203-13 |year= 2002 |pmid= 11891061 |doi= }}
*{{cite journal | author=Nelson G, Chandrashekar J, Hoon MA, ''et al.'' |title=An amino-acid taste receptor. |journal=Nature |volume=416 |issue= 6877 |pages= 199-202 |year= 2002 |pmid= 11894099 |doi= 10.1038/nature726 }}
*{{cite journal | author=Li X, Staszewski L, Xu H, ''et al.'' |title=Human receptors for sweet and umami taste. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 7 |pages= 4692-6 |year= 2002 |pmid= 11917125 |doi= 10.1073/pnas.072090199 }}
*{{cite journal | author=Liao J, Schultz PG |title=Three sweet receptor genes are clustered in human chromosome 1. |journal=Mamm. Genome |volume=14 |issue= 5 |pages= 291-301 |year= 2003 |pmid= 12856281 |doi= 10.1007/s00335-002-2233-0 }}
*{{cite journal | author=Xu H, Staszewski L, Tang H, ''et al.'' |title=Different functional roles of T1R subunits in the heteromeric taste receptors. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 39 |pages= 14258-63 |year= 2005 |pmid= 15353592 |doi= 10.1073/pnas.0404384101 }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal | author=Sainz E, Cavenagh MM, LopezJimenez ND, ''et al.'' |title=The G-protein coupling properties of the human sweet and amino acid taste receptors. |journal=Dev Neurobiol |volume=67 |issue= 7 |pages= 948-59 |year= 2007 |pmid= 17506496 |doi= 10.1002/dneu.20403 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on TAS1R2... {November 26, 2007 2:31:50 PM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {November 26, 2007 2:33:55 PM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Taste receptor, type 1, member 2
| HGNCid = 14905
| Symbol = TAS1R2
| AltSymbols =; TR2; GPR71; T1R2
| OMIM = 606226
| ECnumber =
| Homologene = 75323
| MGIid = 1933546
| GeneAtlas_image1 = PBB_GE_TAS1R2_gnf1h06475_at_tn.png
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0008067 |text = metabotropic glutamate, GABA-B-like receptor activity}} {{GNF_GO|id=GO:0008527 |text = taste receptor activity}} {{GNF_GO|id=GO:0046982 |text = protein heterodimerization activity}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}} {{GNF_GO|id=GO:0050916 |text = sensory perception of sweet taste}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 80834
| Hs_Ensembl = ENSG00000179002
| Hs_RefseqProtein = NP_689418
| Hs_RefseqmRNA = NM_152232
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 1
| Hs_GenLoc_start = 19038680
| Hs_GenLoc_end = 19058763
| Hs_Uniprot = Q8TE23
| Mm_EntrezGene = 83770
| Mm_Ensembl =
| Mm_RefseqmRNA = XM_980714
| Mm_RefseqProtein = XP_985808
| Mm_GenLoc_db =
| Mm_GenLoc_chr =
| Mm_GenLoc_start =
| Mm_GenLoc_end =
| Mm_Uniprot =
}}
}}
'''Taste receptor, type 1, member 2''', also known as '''TAS1R2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TAS1R2 taste receptor, type 1, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80834| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text =
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Chandrashekar J, Hoon MA, Ryba NJ, Zuker CS |title=The receptors and cells for mammalian taste. |journal=Nature |volume=444 |issue= 7117 |pages= 288-94 |year= 2007 |pmid= 17108952 |doi= 10.1038/nature05401 }}
*{{cite journal | author=Hoon MA, Adler E, Lindemeier J, ''et al.'' |title=Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity. |journal=Cell |volume=96 |issue= 4 |pages= 541-51 |year= 1999 |pmid= 10052456 |doi= }}
*{{cite journal | author=Li X, Staszewski L, Xu H, ''et al.'' |title=Human receptors for sweet and umami taste. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 7 |pages= 4692-6 |year= 2002 |pmid= 11917125 |doi= 10.1073/pnas.072090199 }}
*{{cite journal | author=Spadaccini R, Trabucco F, Saviano G, ''et al.'' |title=The mechanism of interaction of sweet proteins with the T1R2-T1R3 receptor: evidence from the solution structure of G16A-MNEI. |journal=J. Mol. Biol. |volume=328 |issue= 3 |pages= 683-92 |year= 2003 |pmid= 12706725 |doi= }}
*{{cite journal | author=Liao J, Schultz PG |title=Three sweet receptor genes are clustered in human chromosome 1. |journal=Mamm. Genome |volume=14 |issue= 5 |pages= 291-301 |year= 2003 |pmid= 12856281 |doi= 10.1007/s00335-002-2233-0 }}
*{{cite journal | author=Zhao GQ, Zhang Y, Hoon MA, ''et al.'' |title=The receptors for mammalian sweet and umami taste. |journal=Cell |volume=115 |issue= 3 |pages= 255-66 |year= 2004 |pmid= 14636554 |doi= }}
*{{cite journal | author=Galindo-Cuspinera V, Winnig M, Bufe B, ''et al.'' |title=A TAS1R receptor-based explanation of sweet 'water-taste'. |journal=Nature |volume=441 |issue= 7091 |pages= 354-7 |year= 2006 |pmid= 16633339 |doi= 10.1038/nature04765 }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal | author=Behrens M, Bartelt J, Reichling C, ''et al.'' |title=Members of RTP and REEP gene families influence functional bitter taste receptor expression. |journal=J. Biol. Chem. |volume=281 |issue= 29 |pages= 20650-9 |year= 2006 |pmid= 16720576 |doi= 10.1074/jbc.M513637200 }}
}}
{{refend}}
{{protein-stub}}
end log.
