- INFO: Beginning work on ARID3B... {December 20, 2007 11:13:49 AM PST}
- REDIRECT: Protein Redirected to: ARID3B {December 20, 2007 11:15:27 AM PST}
- CREATED: Created new protein page: ARID3B {December 20, 2007 11:15:34 AM PST}
- INFO: Beginning work on CENPE... {December 20, 2007 11:09:50 AM PST}
- REDIRECT: Protein Redirected to: CENPE {December 20, 2007 11:10:14 AM PST}
- UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 11:10:16 AM PST}
- UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 11:10:16 AM PST}
- UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 11:10:16 AM PST}
- UPDATED: Updated protein page: CENPE {December 20, 2007 11:10:24 AM PST}
- INFO: Beginning work on HSPH1... {December 20, 2007 11:18:50 AM PST}
- REDIRECT: Protein Redirected to: HSPH1 {December 20, 2007 11:19:10 AM PST}
- UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 11:19:12 AM PST}
- UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 11:19:12 AM PST}
- UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 11:19:12 AM PST}
- UPDATED: Updated protein page: HSPH1 {December 20, 2007 11:19:18 AM PST}
- INFO: Beginning work on MYBBP1A... {December 20, 2007 11:10:24 AM PST}
- REDIRECT: Protein Redirected to: MYBBP1A {December 20, 2007 11:10:41 AM PST}
- UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 11:10:43 AM PST}
- UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 11:10:43 AM PST}
- UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 11:10:43 AM PST}
- UPDATED: Updated protein page: MYBBP1A {December 20, 2007 11:10:51 AM PST}
- INFO: Beginning work on NOL5A... {December 20, 2007 11:10:51 AM PST}
- REDIRECT: Protein Redirected to: NOL5A {December 20, 2007 11:12:27 AM PST}
- CREATED: Created new protein page: NOL5A {December 20, 2007 11:12:37 AM PST}
- INFO: Beginning work on NUP50... {December 20, 2007 11:16:26 AM PST}
- REDIRECT: Protein Redirected to: NUP50 {December 20, 2007 11:18:01 AM PST}
- CREATED: Created new protein page: NUP50 {December 20, 2007 11:18:09 AM PST}
- INFO: Beginning work on POLQ... {December 20, 2007 11:15:34 AM PST}
- REDIRECT: Protein Redirected to: POLQ {December 20, 2007 11:16:17 AM PST}
- CREATED: Created new protein page: POLQ {December 20, 2007 11:16:26 AM PST}
- INFO: Beginning work on POP1... {December 20, 2007 11:19:44 AM PST}
- REDIRECT: Protein Redirected to: POP1 (gene) {December 20, 2007 11:20:28 AM PST}
- CREATED: Created new protein page: POP1 (gene) {December 20, 2007 11:20:37 AM PST}
- INFO: Beginning work on RPP40... {December 20, 2007 11:18:09 AM PST}
- REDIRECT: Protein Redirected to: RPP40 {December 20, 2007 11:18:42 AM PST}
- CREATED: Created new protein page: RPP40 {December 20, 2007 11:18:50 AM PST}
- INFO: Beginning work on SPAG5... {December 20, 2007 11:12:37 AM PST}
- REDIRECT: Protein Redirected to: SPAG5 {December 20, 2007 11:13:42 AM PST}
- CREATED: Created new protein page: SPAG5 {December 20, 2007 11:13:49 AM PST}
- INFO: Beginning work on STIP1... {December 20, 2007 11:20:37 AM PST}
- UPLOAD: Added new Image to wiki: File:PBB Protein STIP1 image.jpg {December 20, 2007 11:21:31 AM PST}
- REDIRECT: Page directory gave bad page (Hop (protein)). Continuing with search.. Please correct entry: <10963,Hop (protein)>. {December 20, 2007 11:21:39 AM PST}
- AMBIGUITY: Did not locate an acceptable page to update. {December 20, 2007 11:21:53 AM PST}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image = PBB_Protein_STIP1_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1elr.
| PDB = {{PDB2|1elr}}, {{PDB2|1elw}}
| Name = Stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein)
| HGNCid = 11387
| Symbol = STIP1
| AltSymbols =; HOP; P60; IEF-SSP-3521; STI1L
| OMIM = 605063
| ECnumber =
| Homologene = 4965
| MGIid = 109130
| GeneAtlas_image1 = PBB_GE_STIP1_213330_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_STIP1_212009_s_at_tn.png
| Function = {{GNF_GO|id=GO:0005488 |text = binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005794 |text = Golgi apparatus}}
| Process = {{GNF_GO|id=GO:0006950 |text = response to stress}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 10963
| Hs_Ensembl = ENSG00000168439
| Hs_RefseqProtein = NP_006810
| Hs_RefseqmRNA = NM_006819
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 63709320
| Hs_GenLoc_end = 63728591
| Hs_Uniprot = P31948
| Mm_EntrezGene = 20867
| Mm_Ensembl = ENSMUSG00000024966
| Mm_RefseqmRNA = NM_016737
| Mm_RefseqProtein = NP_058017
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 19
| Mm_GenLoc_start = 7088143
| Mm_GenLoc_end = 7102755
| Mm_Uniprot = Q3THQ5
}}
}}
'''Stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein)''', also known as '''STIP1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: STIP1 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10963| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text =
}}
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Rasmussen HH, van Damme J, Puype M, ''et al.'' |title=Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. |journal=Electrophoresis |volume=13 |issue= 12 |pages= 960-9 |year= 1993 |pmid= 1286667 |doi= }}
*{{cite journal | author=Honoré B, Leffers H, Madsen P, ''et al.'' |title=Molecular cloning and expression of a transformation-sensitive human protein containing the TPR motif and sharing identity to the stress-inducible yeast protein STI1. |journal=J. Biol. Chem. |volume=267 |issue= 12 |pages= 8485-91 |year= 1992 |pmid= 1569099 |doi= }}
*{{cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi= }}
*{{cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791-806 |year= 1997 |pmid= 8889548 |doi= }}
*{{cite journal | author=Dittmar KD, Pratt WB |title=Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformation. |journal=J. Biol. Chem. |volume=272 |issue= 20 |pages= 13047-54 |year= 1997 |pmid= 9148915 |doi= }}
*{{cite journal | author=Dittmar KD, Demady DR, Stancato LF, ''et al.'' |title=Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70. |journal=J. Biol. Chem. |volume=272 |issue= 34 |pages= 21213-20 |year= 1997 |pmid= 9261129 |doi= }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi= }}
*{{cite journal | author=Zou J, Guo Y, Guettouche T, ''et al.'' |title=Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1. |journal=Cell |volume=94 |issue= 4 |pages= 471-80 |year= 1998 |pmid= 9727490 |doi= }}
*{{cite journal | author=Scanlan MJ, Gordan JD, Williamson B, ''et al.'' |title=Antigens recognized by autologous antibody in patients with renal-cell carcinoma. |journal=Int. J. Cancer |volume=83 |issue= 4 |pages= 456-64 |year= 1999 |pmid= 10508479 |doi= }}
*{{cite journal | author=Scheufler C, Brinker A, Bourenkov G, ''et al.'' |title=Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine. |journal=Cell |volume=101 |issue= 2 |pages= 199-210 |year= 2000 |pmid= 10786835 |doi= 10.1016/S0092-8674(00)80830-2 }}
*{{cite journal | author=Hernández MP, Chadli A, Toft DO |title=HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor. |journal=J. Biol. Chem. |volume=277 |issue= 14 |pages= 11873-81 |year= 2002 |pmid= 11809754 |doi= 10.1074/jbc.M111445200 }}
*{{cite journal | author=Brinker A, Scheufler C, Von Der Mulbe F, ''et al.'' |title=Ligand discrimination by TPR domains. Relevance and selectivity of EEVD-recognition in Hsp70 x Hop x Hsp90 complexes. |journal=J. Biol. Chem. |volume=277 |issue= 22 |pages= 19265-75 |year= 2002 |pmid= 11877417 |doi= 10.1074/jbc.M109002200 }}
*{{cite journal | author=Zanata SM, Lopes MH, Mercadante AF, ''et al.'' |title=Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection. |journal=EMBO J. |volume=21 |issue= 13 |pages= 3307-16 |year= 2002 |pmid= 12093732 |doi= 10.1093/emboj/cdf325 }}
*{{cite journal | author=Hernández MP, Sullivan WP, Toft DO |title=The assembly and intermolecular properties of the hsp70-Hop-hsp90 molecular chaperone complex. |journal=J. Biol. Chem. |volume=277 |issue= 41 |pages= 38294-304 |year= 2002 |pmid= 12161444 |doi= 10.1074/jbc.M206566200 }}
*{{cite journal | author=Abbas-Terki T, Briand PA, Donzé O, Picard D |title=The Hsp90 co-chaperones Cdc37 and Sti1 interact physically and genetically. |journal=Biol. Chem. |volume=383 |issue= 9 |pages= 1335-42 |year= 2003 |pmid= 12437126 |doi= }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Imai Y, Soda M, Murakami T, ''et al.'' |title=A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death. |journal=J. Biol. Chem. |volume=278 |issue= 51 |pages= 51901-10 |year= 2004 |pmid= 14532270 |doi= 10.1074/jbc.M309655200 }}
*{{cite journal | author=Longshaw VM, Chapple JP, Balda MS, ''et al.'' |title=Nuclear translocation of the Hsp70/Hsp90 organizing protein mSTI1 is regulated by cell cycle kinases. |journal=J. Cell. Sci. |volume=117 |issue= Pt 5 |pages= 701-10 |year= 2004 |pmid= 14754904 |doi= 10.1242/jcs.00905 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Rush J, Moritz A, Lee KA, ''et al.'' |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94-101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046 }}
}}
{{refend}}
{{protein-stub}}
- INFO: Beginning work on TCERG1... {December 20, 2007 11:19:18 AM PST}
- REDIRECT: Protein Redirected to: TCERG1 {December 20, 2007 11:19:37 AM PST}
- UPDATE PROTEIN BOX: Updating Protein Box, No errors. {December 20, 2007 11:19:38 AM PST}
- UPDATE SUMMARY: Updating Summary, No Errors. {December 20, 2007 11:19:38 AM PST}
- UPDATE CITATIONS: Updating Citations, No Errors. {December 20, 2007 11:19:38 AM PST}
- UPDATED: Updated protein page: TCERG1 {December 20, 2007 11:19:44 AM PST}
end log.
