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John Joseph Holland is

General Information

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John Joseph Holland is an American virologist, author of hundreds of original scientific papers and the main scientist responsible for the discovery of cell-surface polio-virus receptors for which he was awarded the American Society for Microbiology's Eli Lilly and Company Research Award in 1963.

Parents

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George and Colleta (maiden name Coin) Holland were born in the late nineteenth century in America, both as third generation Irish immigrants of the Potato Famine. George was a soldier in World War One and also an accomplished amateur boxer who was a friend and contemporary of Jack Dempsey, the great boxer.

Birth

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John Joseph Holland was the first child born to Colleta and George Holland on November 16, 1929 in Pittsburg, PA. He has three bothers, Richard, George and Robert and one sister, Mary (married name Frieze. Richard Holland died in 2004 and the remainder of Dr. Holland's siblings are living.

Move to Los Angeles

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John Holland moved with his parents to Los Angeles, California in 1944 and attended college at the Jesuit University of Loyola Marymount College.

Service in the Korean War

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John Holland and his brother Richard served as infantrymen in Korea from 1950 to 1952. John Holland served as Seargant and was involved in numerous wintertime battles in what is now North Korea.

Graduate School at UCLA

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John Holland was accepted to the University of California at Los Angeles' graduate program in the department of microbiology in 1954. He worked in the laboratory of MJ Pickett and recieved his PhD in 1958.

Post-Doctoral Fellowship at the University of Minnesota

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John Holland performed his post doctoral work in the laboratory of Jerome T. Syverton at the University of Minnesota from 1958 to 1960. During that time, Dr. Holland performed experimental work upon human viruses, especially the polio-virus. He left Minnesota in 1960 to take a job as assistant professor of biology at the University of Washington in Seattle.

ASM Eli Lilly and Company Research Award: 1963

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Dr. Holland was the 1963 laureate of the American Society for Microbiology Eli Lilly and Company Research Award. The ASM describes this award as " ASM's oldest and most prestigious prize, it rewards fundamental research of unusual merit in microbiology or immunology by an individual on the threshold of his or her career." Dr. Holland won the award for his work on mammalian cell-virus relationships demonstrating that mammalian cells were susceptible to poliovirus because they carried on the cell-surface a protein 'receptor' and that the immunity of non-mammalian cells could be overcome by exposing them to naked polioviral RNA. This work established the basic mechanisms of virus-cell affinities and underlies much of modern bio-medical virology.

Marriage

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John Holland met his future wife Dorothy Delaney first met at the Newman Club at UCLA in 1956. The two dated until John departed for Minneapolis in late 1956 at which time they began a steady long-distance relationship the culminated in their marriage in 1960 in Los Angeles. Dorothy Holland worked in insurance and later real estate while raising children.

Children

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John and Dorothy Holland have two children, Mark and Lynn born April 22, 1963 and May 24, 1964 respectively. Both children are living. Mark Holland is a medical doctor practicing in Albuquerque, New Mexico and is single with no children. Lynn Moe-Holland is a California State Park Ranger living in San Clemente, California with her husband Sean and two daughters Molly and Megan.

Work on 'Error Catastrophe'

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John Holland disproved a leading theory of cellular aging called 'error catastrophe' in a single experiment and published the result in a brief article in the journal Nature in 1971.


References

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References

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