Wikipedia

TinyAtoms

Joined 5 July 2018

I am excited to be part of the Wikipedia Fellows program which is designed to train subject-area experts how to contribute to Wikipedia. Wiki Education facilitates this program. Learn more at http://fellows.wikiedu.org. All of my contributions are my own and I take responsibility for them.

Improving pages for Women in Science

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The goal of reducing gender bias in the representation of women scientists and their accomplishments.

Improving Susan Lindquist's page

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  1. Split "Research" and "Career" into separate sections.
  2. Research contributions
    1. Heat shock proteins HSP. Prions. Chaperones as "evolutionary capacitors".
    2. Non-mendelian inheritance. (Lamarckian). Prions catalyze conformational change of other prions.
    3. Helped answer long-standing puzzle about changes in how environmental stress leads to changes in phenotype.
  3. Career
    1. Lindquist was an entrepreneur. Co-founded FoldX with Jeff Kelly. FoldX commercialized Tamifidis, now sold by Pfizer. Co-founded Yumanity with Tony Coles.
    2. Contextualize awards if it is documented. "Won X for contributions to Y."

Sources

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  1. Obituaries
    1. Elaine Fuchs Cell Journal [1]
    2. Jeffery Kelly and Richard Morimoto ASBMB Journal [2]
    3. William Grimes New York Times [3]
    4. Brook Bevis Journal of Cell Biology [4]
    5. Vivian Siegel Disease Models and Mechanisms [5]
    6. James Shorter and Aaron Gitler Naure [6]
    7. (paywall) Boston Globe [7]
  2. Interviews
    1. Kristin Kain Disease Models and Mechanisms [8]
    2. Public Library of Science [9]
    3. The Scientist Magazine [10]
  3. Newspaper Articles
    1. "On the trail of Parkinson's, through Yeast" New York Times[11]
  4. Journal Articles
    1. Lindquist's work with yeast prions has provided significant evidence that supports a role for proteins in evolution (evolution is not exclusively DNA).[12]

Sandbox

  • and went on to show that which had been known to aggregate in several neurodegenerative diseases, used by cells to burst of novel phenotypes. This provided crucial evidence that proteins heritable traits.

References

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  1. ^ Fuchs, Elaine (2016-12). "Susan Lee Lindquist (1949–2016)". Cell. 167 (6): 1440–1442. doi:10.1016/j.cell.2016.11.030. ISSN 0092-8674. {{cite journal}}: Check date values in: |date= (help)
  2. ^ Kelly, Jeffery; Morimoto, Richard (March 1 2017). "Retrospective | Susan Lindquist (1949 – 2016)". www.asbmb.org. Retrieved 2018-07-31. {{cite web}}: Check date values in: |date= (help); Cite has empty unknown parameter: |dead-url= (help)
  3. ^ Grimes, William (Oct 28 2016). "Susan Lindquist, Scientist Who Made Genetic Discoveries Using Yeast, Dies at 67". Retrieved 2018-07-31. {{cite news}}: Check date values in: |date= (help)
  4. ^ Bevis, Brooke J. (2016-12-24). "Susan Lindquist: Visionary scientist and peerless mentor". J Cell Biol: jcb.201612112. doi:10.1083/jcb.201612112. ISSN 0021-9525. PMID 28028126.
  5. ^ Siegel, Vivian (2017-01-01). "Susan Lindquist: a tribute". Disease Models & Mechanisms. 10 (1): 1–2. doi:10.1242/dmm.028696. ISSN 1754-8403. PMID 28067627.
  6. ^ Shorter, James; Gitler, Aaron D. (2016-12). "Susan Lee Lindquist (1949–2016)". Nature. 540 (7631): 40–40. doi:10.1038/540040a. ISSN 0028-0836. {{cite journal}}: Check date values in: |date= (help)
  7. ^ "Susan Lindquist, former director Whitehead Institute for Biomedical Research and National Medal of Science winner, dies at 67 - The Boston Globe". BostonGlobe.com. Retrieved 2018-07-31.
  8. ^ Kain, Kristin (2008-07-01). "Using yeast to understand protein folding diseases: an interview with Susan Lindquist". Disease Models & Mechanisms. 1 (1): 17–19. doi:10.1242/dmm.000810. ISSN 1754-8403. PMID 19048046.
  9. ^ Gitschier, Jane (2011-05-12). "A Flurry of Folding Problems: An Interview with Susan Lindquist". PLOS Genetics. 7 (5): e1002076. doi:10.1371/journal.pgen.1002076. ISSN 1553-7404. PMC 3093363. PMID 21589898.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
  10. ^ Azvolinsky, Anna (Jan 1 2016). "Fearless about Folding". The Scientist Magazine®. Retrieved 2018-07-31. {{cite web}}: Check date values in: |date= (help); Cite has empty unknown parameter: |dead-url= (help)
  11. ^ Dreifus, Claudia (April 24, 2007). "On the Trail of Parkinson's, Through Yeast Cells". New York Times. Retrieved 2018-08-07.
  12. ^ Bussard, Alain E. (2005-08-01). "A scientific revolution?: The prion anomaly may challenge the central dogma of molecular biology". EMBO reports. 6 (8): 691–694. doi:10.1038/sj.embor.7400497. ISSN 1469-221X. PMID 16065057.
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