I went off Subutex 3 months ago. I don't know how it feels to withdraw from methadone, but I can tell you withdrawing from Subutex is NOT easy nor in any way "mild". The physical part is much like withdrawing from other opiates, it just lasts longer because of it's insanely long half life. The mental part is the hardest. It is true, at least for me, that Sub acts as an extremely good and fast acting anti-depressant. About 10 days after stopping it all hell broke loose. I couldn't stand to smell food or coffee brewing; I lost 10 lbs in 2 weeks, went through about a week of uncontrollable crying over nothing. I could not make myself get out of bed for about 5 days. Then there were the leg cramps, sneezing fits, rapid mood changes and even absolute rage, once again over nothing. It was horrible and the more I read online the more I realize that nobody understands this drug. It has pros and cons, but until you take it for some period (5 years for me) and then stop it you really have no idea of what it is doing to your body and brain. I would LOVE to participate in a study of some sort. The pain management dr I'm seeing now said none of his other patients made it past a month before going back on it. My main reason for stopping was it made my mouth extremely dry and was destroying my teeth. It would feel like glue had been pored in my mouth. And most of the time dry mouth isn't even listed as a side effect. — Preceding unsigned comment added by 50.147.164.235 (talk) 06:08, 21 August 2013 (UTC)Reply