Protein Chemist

Short Biography: My graduate training has been a slightly odd mixture of structural and computational biology & physical and analytical methods. I also know a thing or two about polymers. Go figure.

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This line is a test (+)H₃N-Protein\Chemist-CO₂(-) 12:25, 8 September 2011 (UTC)

DelPhi (software)

Sorry about the false positive with ClueBot...sometimes it just doesn't have a clue! Please report the false positive here, so that it can be fixed. WikiPuppies! (bark) 14:14, 31 August 2011 (UTC)

Already done. Thanks--I(q) = User(q)·Talk(q) 14:15, 31 August 2011 (UTC)

You're very welcome. WikiPuppies! (bark) 14:16, 31 August 2011 (UTC)

Nice sig-line

:) DMacks (talk) 16:14, 9 September 2011 (UTC)

Thanks. I'm not really a Zwitterion but I play one on TV Wikipedia. (+)H₃N-Protein\Chemist-CO₂(-) 19:26, 9 September 2011 (UTC)

Thankyou

for the headsup / legup / input . . I've zoomed through the tutorial, and will catch up on the content-stuff another time hopefully soon. SquisherDa (talk) 01:14, 10 February 2012 (UTC)

Re:New image for WikiProject Polymers Banner

Please go ahead. Thanks you so much for your consideration in helping us.···Vanischenu^「m/_Talk」 14:41, 5 February 2013 (UTC)

Beta amyloid

Thank you for your note about Aβ42. It would be nice to have an unambiguous definition of protein. Our definition, on Wikipedia, is still ambiguous, even after my edits. In other words, not any chain of aminoacids is a protein, but we do not have an unambiguous definition which allows us to distinguish between:

1. a polypeptide which is also a protein and
2. a polypeptide which is not a protein (i.e. a plain "peptide").

It would be nice if we could say that a protein is a polypeptide that is codified by DNA of some living organism, while a peptide is not (being for example the product of the degradation of a protein by means of a protease)... which would be unambiguous, but I cannot find this definition in the literature. If you want to discuss this, you can do it here. I am monitoring your page. Regards, Paolo.dL (talk) 13:14, 2 May 2014 (UTC)

It's tricky, there really isn't any single clear definition in the literature to draw from. For instance "unstructured polypeptide" and "intrinsically disordered protein" basically mean the same thing. I think the most relevant parameter should be whether a polypeptide posses secondary and tertiary structure, unfortunately there are decades worth of conflicting definitions of "peptide" vs "protein" in the way of that. Also, for what it's worth small peptides can be genetically encoded too, so that doesn't really work either. (+)H₃N-Protein\Chemist-CO₂(-) 14:10, 2 May 2014 (UTC)

Interesting. Thanks. Paolo.dL (talk) 15:00, 2 May 2014 (UTC)

It's there. THe aim is preponderance of reliable secondary and tertiary sourcing. Take all the v good/classic grad texts you can—Branden and Tooze, Creighton, Fersht, Robert Copeland, Cantor and Schimmel, etc—read the relevant intro sections, and just write it. You'll get feedback. You two have the background. Cheers. Le Prof Leprof 7272 (talk) 01:46, 12 June 2014 (UTC)

Re

Hi, i guess you are right with your edit summary, however, the main point were about the other edits, which you apparently reverted. Are you suggesting that oligopeptides, with only a few amino acids are also called polypeptides, which are defined to have many amino acids? prokaryotes (talk) 02:02, 18 August 2014 (UTC)

The wording was a little odd, couldn't exactly tell what you were getting at as originally written. You're welcome to reinsert your edit with the revised terminology, but consider that you'd basically be writing "a polypeptide [..] can contain many peptide bonds", which does sound a little circular. (+)H₃N-Protein\Chemist-CO₂(-) 02:11, 18 August 2014 (UTC)

I've to admit that im learning chemistry as i go along, so sometimes errors such as these happen, especially when sources are scarce, thanks for your response. I will try to bring it more in line with this reference http://www.biology-online.org/dictionary/Polypeptide prokaryotes (talk) 02:15, 18 August 2014 (UTC)

No worries.(+)H₃N-Protein\Chemist-CO₂(-) 17:33, 18 August 2014 (UTC)

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