User talk:EKeller/sandbox

Latest comment: 8 years ago by Karkeraa

Hi Eleanor, Great draft. One major point I would like to see discussed is the actual definition of genetic heterogeneity. It would be useful for readers to just have this basic definition to refer to if they get confused. Another important addition to make is the use of links to other pages. This way, you don't have to explain what you think should be known to the readers- rather they can read up on it at an already existing page. I think phenotype is used frequently, though, so it warrants a small definition as well. Lastly, the sources seem to be disorganized or an error occurred at the bottom of your sandbox. That's an easy fix! The in-text citations look good though.

Smaller things to think about: maybe change the sentence that has "differently in different individuals", so that the sentence doesn't have the repeating "differents". Under the occurrence section you repeat the three disorders that were also stated in the beginning. I just want to make sure you go into more detail. Otherwise this section is unnecessary because you already introduced it; we just need more detail now.

Again, great encyclopedic work!AJAndes (talk) 22:10, 1 December 2015 (UTC)Reply

Peer Review:

The author is aiming to write about genetic heterogeneity, a condition in which genes vary from the norm of the population. Furthermore, the author writes about how gene abnormalities can cause medical diseases, specifically mental illness, autism, cystic fibrosis, and Retinitis Pigmentosa. The author specifies that these diseases are caused by allelic heterogeneity, when there are multiple mutations in a single gene locus. The multiple alleles that are formed because of this heterogeneity cause the same phenotype (the same outside expression) of the genes and thus produce the same medical disease or disorder.

I enjoyed reading this article. Overall I don't think there are any major problems with formatting, grammar, or punctuation.

The subheadings under the Occurrence heading need to be filled in, but other than that the rest of the headings are a good start and have a decent amount of new information that is being added to Wikipedia.

There are no citations for the information under the Mechanisms of Mutations heading. Adding these citations and adding at least one diagram or visual to this article improve it immensely, as it will be easier for the reader to gain more context and understand the complexities about this topic, as well as allow the opportunity for further reading on the subject.

The article is thoughtful and well written. The addition of more citations and more sections, if possible, would make it perfect and ready for final submission. Keep up the good work! Karkeraa (talk) 00:53, 7 December 2015 (UTC)Reply