Marcelo1229

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Low-dose naltrexone

You seem to subscribe to the benefits of low-dose naltrexone in all sorts of diseases (MS and cancer? wow). If this is worth mentioning (and I'm not sure it is) could you do this in the form of original content, and not long lists of external links? You could also provide more of an explanation on the naltrexone page on its supposed mechanism of action in all those disorders. JFW | T@lk 10:29, 26 Jun 2005 (UTC)

Pawpaw and anti-cancer drugs

I noticed that you added a link to pawpaw on the cancer page. Going through your contributions you seem to know a lot about lots of compounds that are purportedly antineoplastic. Many of your additions in this area suffer from very poor sourcing, while others are completely unsubstantiated. In the case of low dose naltrexone, the only source I can find is a single patient study (PMID 16484716), surely not enough to base a claim on. This trial has not been published, hence its consistency cannot be tested. Using a drug for such a large number of different cancers is rather un-mainstream and unlikely to be taken seriously by oncologists.

I'm very interested to know what you hope to achieve. JFW | T@lk 14:55, 5 April 2007 (UTC)

I've responded to your post on my talkpage. Please try to remain civil. JFW | T@lk 06:25, 8 April 2007 (UTC)

Chile city naming convention poll

You are invited to participate in a poll at Wikipedia talk:Chile-related regional notice board#settlement article naming poll. Please express your opinion there. Jespinos 17:24, 6 May 2007 (UTC)

Redirects

Hi there - I added a redirect for you, see [1]. Cheers, --HappyCamper 02:59, 12 June 2007 (UTC)

External links

You are again reminded not to flood articles with external links, as you have done on curcumin. Links are the least important part of a Wikipedia article (everyone can use Google). Instead, please contribute well-sourced, neutral and reliable encyclopedia content. Thank you. JFW | T@lk 16:55, 7 November 2007 (UTC)

Fatigue in cancer

Thanks for adding mention of fatigue in cancer. The article neglected to mention this despite much talk about it. However, I have temporarily removed the use of amphetamines, as this seems to me a premature statement. Instead, perhaps we could mention L-carnitine, bupropion, modafinil and SSRIs, per the review in PMID 17573455. Let me know what you think. JFW | T@lk 23:40, 3 January 2008 (UTC)

I do not have any personal commitment to the specifics on cancer-fatigue treatment, but I believe it would be useful for patients, and fair to the subject, to write something that at least some psycho-stimulants can be useful for treatment of cancer-fatigue. An article by the U.S. National Cancer Institute [2] states the following (among other things):

"Psychostimulants

Although fatigue is one of the most prevalent symptoms in cancer, to date few trials are published on the use of psychostimulants as a treatment for fatigue in people with cancer. The support for their use arises largely from clinical anecdotal experience. Psychostimulants (caffeine, methylphenidate, modafinil, and dextroamphetamine) given in low doses are useful for patients who are suffering from depressed mood, apathy, decreased energy, poor concentration, and weakness. Extensive clinical experience with cancer patients indicates that psychostimulants promote a sense of well-being, decreased fatigue, and increased appetite."

Another reputable source on cancer (from cancer.org) has at least two links on Ritalin treatment for cancer-fatigue: [3] and [4]

regards, marcelo1229; Jan3, 08; 19:15 US-PST Marcelo1229 (talk) 04:50, 4 January 2008 (UTC)

Dichloroacetic Acid

Hi Marcelo, I didn't mean to, but I seem to have stirred the pot on the DCA page. I added an external link to the updated data at Medicor Cancer Clinic (after the link you added in April '08). Someone took exception to that and has now removed both external links. See discussion here Medicor External Links Just thought you might appreciate the heads up. Thanks - P.S. I like the LDN page. Libertytorch (talk) 06:06, 4 January 2009 (UTC)

ArbCom elections are now open!

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