Vacuolar protein sorting-associated protein 52 homolog is a protein that in humans is encoded by the VPS52 gene.[5][6]

VPS52
Identifiers
AliasesVPS52, ARE1, SAC2, SACM2L, dJ1033B10.5, GARP complex subunit, VPS52 subunit of GARP complex
External IDsOMIM: 603443; MGI: 1330304; HomoloGene: 5756; GeneCards: VPS52; OMA:VPS52 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001289174
NM_001289175
NM_001289176
NM_022553

NM_172620
NM_001357329
NM_001357330
NM_001379410
NM_001379411

RefSeq (protein)

NP_001276103
NP_001276104
NP_001276105
NP_072047

NP_766208
NP_001344258
NP_001344259
NP_001366339
NP_001366340

Location (UCSC)Chr 6: 33.25 – 33.27 MbChr 17: 34.17 – 34.19 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18.[6]

References

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  1. ^ a b c ENSG00000206286, ENSG00000223501, ENSG00000224455, ENSG00000225590, ENSG00000223618, ENSG00000228425 GRCh38: Ensembl release 89: ENSG00000236014, ENSG00000206286, ENSG00000223501, ENSG00000224455, ENSG00000225590, ENSG00000223618, ENSG00000228425Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024319Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Walter L, Gunther E (Dec 1998). "Identification of a novel highly conserved gene in the centromeric part of the major histocompatibility complex". Genomics. 52 (3): 298–304. doi:10.1006/geno.1998.5463. PMID 9790748.
  6. ^ a b "Entrez Gene: VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)".

Further reading

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