VPS72

VPS72
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5FUG
Identifiers
Aliases	VPS72, CFL1, Swc2, TCFL1, YL-1, YL1, vacuolar protein sorting 72 homolog
External IDs	OMIM: 600607; MGI: 1202305; HomoloGene: 110905; GeneCards: VPS72; OMA:VPS72 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	151,195,321 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	95,030,362 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; ganglionic eminence; ; ventricular zone; ; Achilles tendon; ; gastrocnemius muscle; ; islet of Langerhans; ; muscle of thigh; ; smooth muscle tissue; ; stromal cell of endometrium; ; prefrontal cortex;
	Top expressed in
	ventricular zone; ; muscle of thigh; ; medial ganglionic eminence; ; neural tube; ; zygote; ; lip; ; internal carotid artery; ; external carotid artery; ; neural layer of retina; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; histone binding;
Cellular component	nucleus; nucleoplasm; nuclear speck; protein-containing complex;
Biological process	chromatin remodeling; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; somatic stem cell population maintenance; transcription, DNA-templated; histone exchange; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	6944
	21427
	ENSG00000163159
	ENSMUSG00000008958
	Q15906
	Q62481
	NM_005997; NM_001271087; NM_001271088
	NM_009336
	NP_001258016; NP_001258017; NP_005988
	NP_033362
	Wikidata
View/Edit Human	View/Edit Mouse

Vacuolar protein sorting-associated protein 72 homolog is a protein that in humans is encoded by the VPS72 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000163159 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000008958 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Horikawa I, Tanaka H, Yuasa Y, Suzuki M, Oshimura M (Mar 1995). "Molecular cloning of a novel human cDNA on chromosome 1q21 and its mouse homolog encoding a nuclear protein with DNA-binding ability". Biochemical and Biophysical Research Communications. 208 (3): 999–1007. doi:10.1006/bbrc.1995.1433. PMID 7702631.
^ "Entrez Gene: VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)".

Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (Oct 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Cai Y, Jin J, Florens L, Swanson SK, Kusch T, Li B, Workman JL, Washburn MP, Conaway RC, Conaway JW (Apr 2005). "The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes". The Journal of Biological Chemistry. 280 (14): 13665–70. doi:10.1074/jbc.M500001200. PMID 15647280.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Denoeud F, Kapranov P, Ucla C, Frankish A, Castelo R, Drenkow J, Lagarde J, Alioto T, Manzano C, Chrast J, Dike S, Wyss C, Henrichsen CN, Holroyd N, Dickson MC, Taylor R, Hance Z, Foissac S, Myers RM, Rogers J, Hubbard T, Harrow J, Guigó R, Gingeras TR, Antonarakis SE, Reymond A (Jun 2007). "Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions". Genome Research. 17 (6): 746–59. doi:10.1101/gr.5660607. PMC 1891335. PMID 17567994.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000163159 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000008958 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7702631-5] Horikawa I, Tanaka H, Yuasa Y, Suzuki M, Oshimura M (Mar 1995). "Molecular cloning of a novel human cDNA on chromosome 1q21 and its mouse homolog encoding a nuclear protein with DNA-binding ability". Biochemical and Biophysical Research Communications. 208 (3): 999–1007. doi:10.1006/bbrc.1995.1433. PMID 7702631.

[entrez-6] "Entrez Gene: VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)".

[5]

[6]

[1]

[2]

[3]

[4]

VPS72

References

Further reading