Valerena-4,7(11)-diene synthase

Valerena-4,7(11)-diene synthase (EC 4.2.3.139, VoTPS2) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, valerena-4,7(11)-diene-forming).[1] This enzyme catalyses the following chemical reaction

Valerena-4,7(11)-diene synthase
Identifiers
EC no.4.2.3.139
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
(2E,6E)-farnesyl diphosphate valerena-4,7(11)-diene + diphosphate

This enzyme is isolated from the plant Valeriana officinalis (valerian).

References

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  1. ^ Pyle BW, Tran HT, Pickel B, Haslam TM, Gao Z, MacNevin G, Vederas JC, Kim SU, Ro DK (September 2012). "Enzymatic synthesis of valerena-4,7(11)-diene by a unique sesquiterpene synthase from the valerian plant (Valeriana officinalis)". The FEBS Journal. 279 (17): 3136–46. doi:10.1111/j.1742-4658.2012.08692.x. PMID 22776156. S2CID 205885638.
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