In enzymology, a valine decarboxylase (EC 4.1.1.14) is an enzyme that catalyzes the chemical reaction

valine decarboxylase
Identifiers
EC no.4.1.1.14
CAS no.9031-16-7
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IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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L-valine 2-methylpropanamine + CO2

Hence, this enzyme has one substrate, L-valine, and two products, 2-methylpropanamine and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-valine carboxy-lyase (2-methylpropanamine-forming). Other names in common use include leucine decarboxylase and L-valine carboxy-lyase. It employs one cofactor, pyridoxal phosphate.

References

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  • Sutton CR, King HK (February 1962). "Inhibition of leucine decarboxylase by thiol-binding reagents". Archives of Biochemistry and Biophysics. 96 (2): 360–70. doi:10.1016/0003-9861(62)90421-6. PMID 13918558.