Valine dehydrogenase (NAD+)

Valine dehydrogenase (NAD+) (EC 1.4.1.23) is an enzyme with systematic name L-valine:NAD+ oxidoreductase (deaminating).[1][2] This enzyme catalyses the following chemical reaction

Valine dehydrogenase (NAD+)
Identifiers
EC no.1.4.1.23
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins
L-valine + H2O + NAD+ 3-methyl-2-oxobutanoate + NH3 + NADH + H+

The enzyme from Streptomyces spp. has no activity with NADP+.

See also

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References

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  1. ^ Vancurová I, Vancura A, Volc J, Neuzil J, Flieger M, Basarová G, Bĕhal V (November 1988). "Isolation and characterization of valine dehydrogenase from Streptomyces aureofaciens". Journal of Bacteriology. 170 (11): 5192–6. doi:10.1128/jb.170.11.5192-5196.1988. PMC 211589. PMID 3182727.
  2. ^ Navarrete RM, Vara JA, Hutchinson CR (February 1990). "Purification of an inducible L-valine dehydrogenase of Streptomyces coelicolor A3(2)". Journal of General Microbiology. 136 (2): 273–81. doi:10.1099/00221287-136-2-273. PMID 2324704.
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