Vallejos is a Spanish-language surname, roughly meaning "little valleys". Notable people with the surname include:
- Carlos Vallejos Sologuren (born 1940), Peruvian physician and politician
- Catalina Vallejos (born 1989), Chilean television personality
- Daniel Vallejos (born 1981), Costa Rican footballer
- Fabiana Vallejos (born 1985), Argentine women's footballer
- Leopoldo Vallejos (born 1944), Chilean retired footballer
- Roque Vallejos (1943-2006), Paraguayan poet
- Tomás Vallejos (born 1984), Argentine rugby union player
- Veronica Vallejos (born 1967), Chilean scientist
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