Variecolol is an immunosuppressant/antiviral compound isolated from ascomycete.[1]

Variecolol
Names
IUPAC name
(7E,14S,19S)-5β,25-Epoxy-13,15:14,19-dicyclo-13,14-seco-2α,6α-ophiobola-7,20-dien-5α-ol
Systematic IUPAC name
[1S,2aR,2a1R,4a(5)E,6aS,6bS,7S,9aS,11aR,12aS]-1,9a,11a-Trimethyl-7-(prop-1-en-2-yl)-1,2,2a1,4,6,6a,6b,7,8,9,9a,10,11,11a,12,12a-hexadecahydro-2aH-3-oxapentaleno[1′,6′:4,5,6]cycloocta[1,2-e]inden-2a-ol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C25H38O2/c1-15(2)18-8-9-23(4)10-11-24(5)13-19-16(3)12-25(26)21(19)17(14-27-25)6-7-20(24)22(18)23/h6,16,18-22,26H,1,7-14H2,2-5H3/b17-6-/t16-,18+,19-,20-,21-,22-,23-,24+,25+/m0/s1
    Key: KKLLBIFNYVWKON-HYWMTKJFSA-N
  • C[C@H]1C[C@@]2([C@@H]/3[C@H]1C[C@]4(CC[C@@]5(CC[C@@H]([C@H]5[C@@H]4C/C=C3/CO2)C(=C)C)C)C)O
Properties
C25H38O2
Molar mass 370.577 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

See also

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References

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  1. ^ Fujimoto, H.; Nakamura, E.; Okuyama, E.; Ishibashi, M. (October 2000). "Immunomodulatory constituents from an ascomycete, Emericella aurantio-brunnea". Chemical & Pharmaceutical Bulletin. 48 (10): 1436–1441. doi:10.1248/cpb.48.1436. ISSN 0009-2363. PMID 11045446.